The origin of Amerindians and the peopling of the Americas according to HLA genes: Admixture with Asian and Pacific people

A Arnaiz-Villena, C Parga-Lozano, E Moreno… - Current …, 2010 - ingentaconnect.com
The classical three-waves theory of American peopling through Beringia was based on a
mixed anthropological and linguistic methodology. The use of mtDNA, Y chromosome and …

[HTML][HTML] The immunogenetic diversity of the HLA system in Mexico correlates with underlying population genetic structure

R Barquera, DI Hernández-Zaragoza… - Human Immunology, 2020 - Elsevier
We studied HLA class I (HLA-A,-B) and class II (HLA-DRB1,-DQB1) allele groups and alleles
by PCR-SSP based typing in a total of 15,318 mixed ancestry Mexicans from all the states of …

HLA class I and class II conserved extended haplotypes and their fragments or blocks in Mexicans: implications for the study of genetic diversity in admixed …

J Zúñiga, N Yu, R Barquera, S Alosco, M Ohashi… - PloS one, 2013 - journals.plos.org
Major histocompatibility complex (MHC) genes are highly polymorphic and informative in
disease association, transplantation, and population genetics studies with particular …

Interethnic variability of pharmacogenetic biomarkers in Mexican healthy volunteers: a report from the RIBEF (Ibero-American Network of Pharmacogenetics and …

I Fricke-Galindo, H Jung-Cook, A LLerena… - Drug Metabolism and …, 2016 - degruyter.com
Mexico presents a complex population diversity integrated by Mexican indigenous (MI)(7%
of Mexico's population) and Mexican mestizos (MMs). This composition highlights the …

Remarkably Low KIR and HLA Diversity in Amerindians Reveals Signatures of Strong Purifying Selection Shaping the Centromeric KIR Region

L de Brito Vargas, MH Beltrame, B Ho… - Molecular biology …, 2022 - academic.oup.com
The killer-cell immunoglobulin-like receptors (KIR) recognize human leukocyte antigen
(HLA) molecules to regulate the cytotoxic and inflammatory responses of natural killer cells …

An original Eurasian haplotype, HLA-DRB1* 14: 54-DQB1* 05: 03, influences the susceptibility to idiopathic achalasia

J Furuzawa-Carballeda, J Zuñiga… - PLoS …, 2018 - journals.plos.org
Idiopathic achalasia is a relatively infrequent esophageal motor disorder for which major
histocompatibility complex (MHC) genes are well-identified risk factors. However, no …

[HTML][HTML] Frequency and targeted detection of HLA-DPB1 T cell epitope disparities relevant in unrelated hematopoietic stem cell transplantation

E Zino, L Vago, S Di Terlizzi, B Mazzi, L Zito… - Biology of Blood and …, 2007 - Elsevier
The majority of unrelated donor (UD) hematopoietic stem cell (HSC) transplants are
performed across HLA-DP mismatches, which, if involving disparity in a host-versus-graft …

Do languages and genes correlate?: Some methodological issues

L Campbell - Language Dynamics and Change, 2015 - brill.com
This paper examines aspects of how linguistics and human genetics can collaborate in the
investigation of human prehistory. Matters that need more careful attention for linguistic …

HLA class I and II blocks are associated to susceptibility, clinical subtypes and autoantibodies in Mexican systemic sclerosis (SSc) patients

TS Rodriguez-Reyna, P Mercado-Velázquez, N Yu… - PLoS …, 2015 - journals.plos.org
Introduction Human leukocyte antigen (HLA) polymorphism studies in Systemic Sclerosis
(SSc) have yielded variable results. These studies need to consider the genetic admixture of …

Alleles of HLA-DRB1*04 Associated with Pulmonary Tuberculosis in Amazon Brazilian Population

D Souza de Lima, M Morishi Ogusku… - PLoS …, 2016 - journals.plos.org
Immunogenetic host factors are associated with susceptibility or protection to tuberculosis
(TB). Strong associations of HLA class II genes with TB are reported. We analyzed the HLA …