Cilia are ubiquitous microtubule-based eukaryotic organelles that project from the cell to
generate motility or function in cellular signaling. Motile cilia or flagella contain axonemal …

Dyneins make up a family of AAA+ motors that move toward the minus end of microtubules.
Cytoplasmic dynein is responsible for transporting intracellular cargos in interphase cells …

Cytoplasmic dynein is a microtubule motor vital for cellular organization and division. It
functions as a~ 4-megadalton complex containing its cofactor dynactin and a cargo-specific …

Axonemal dyneins are tethered to doublet microtubules inside cilia to drive ciliary beating, a
process critical for cellular motility and extracellular fluid flow. Axonemal dyneins are …

Cilia are hairlike protrusions that project from the surface of eukaryotic cells and play key
roles in cell signaling and motility. Ciliary motility is regulated by the conserved nexin-dynein …

The intraflagellar transport (IFT) system is a remarkable molecular machine used by cells to
assemble and maintain the cilium, a long organelle extending from eukaryotic cells that …

The assembly and maintenance of most cilia and eukaryotic flagella depends on
intraflagellar transport (IFT), the bidirectional movement of multi-megadalton IFT trains along …

Cilia are thin microtubule‐based protrusions of eukaryotic cells. The swimming of ciliated
protists and sperm cells is propelled by the beating of cilia. Cilia propagate the flow of mucus …

Cilia and mitotic spindles are microtubule (MT)-based, macromolecular machines that
consecutively assemble and disassemble during interphase and M phase of the cell cycle …

Ciliary motility is driven by axonemal dyneins that are assembled in the cytoplasm before
deployment to cilia. Motile ciliopathy can result from defects in the dyneins themselves or …