Brain plasticity in patients with spinal cord injuries: a systematic review

A Calderone, D Cardile, R De Luca… - International Journal of …, 2024 - mdpi.com
A spinal cord injury (SCI) causes changes in brain structure and brain function due to the
direct effects of nerve damage, secondary mechanisms, and long-term effects of the injury …

Prognostic value of tissue bridges in cervical spinal cord injury: a longitudinal, multicentre, retrospective cohort study

D Pfyffer, AC Smith, KA Weber, A Grillhoesl… - The Lancet …, 2024 - thelancet.com
Background The accuracy of prognostication in patients with cervical spinal cord injury (SCI)
needs to be improved. We aimed to explore the prognostic value of preserved spinal tissue …

Spinal cord pathology revealed by MRI in traumatic spinal cord injury

D Pfyffer, P Freund - Current Opinion in Neurology, 2021 - journals.lww.com
Neuroimaging biomarkers reveal focal and remote cord pathology. These biomarkers show
sensitivity to the underlying disease processes and are clinically eloquent. Thus, they …

Transcutaneous electrical spinal cord stimulation to promote recovery in chronic spinal cord injury

C Tefertiller, M Rozwod, E VandeGriend… - Frontiers in …, 2022 - frontiersin.org
Objective: To evaluate the impact of using transcutaneous electrical spinal cord stimulation
(TSCSTSCS) on upper and lower extremity function in individuals with chronic spinal cord …

Spinal cord signal change on magnetic resonance imaging may predict worse clinical in-and outpatient outcomes in patients with spinal cord injury: a prospective …

T Jentzsch, DW Cadotte, JR Wilson, F Jiang… - Journal of clinical …, 2021 - mdpi.com
Prognostic factors for clinical outcome after spinal cord (SC) injury (SCI) are limited but
important in patient management and education. There is a lack of evidence regarding …

Longitudinal motor system changes from acute to chronic spinal cord injury

TM Emmenegger, D Pfyffer, A Curt… - European Journal of …, 2024 - Wiley Online Library
Background and purpose In acute spinal cord injury (SCI), magnetic resonance imaging
(MRI) reveals tissue bridges and neurodegeneration for 2 years. This 5‐year study aims to …

Microstructural plasticity in nociceptive pathways after spinal cord injury

SP Kyathanahally, M Azzarito, J Rosner… - Journal of Neurology …, 2021 - jnnp.bmj.com
Objective To track the interplay between (micro-) structural changes along the trajectories of
nociceptive pathways and its relation to the presence and intensity of neuropathic pain (NP) …

A Silver Lining of Neuropathic Pain: Predicting Favorable Functional Outcome in Spinal Cord Injury

ML Xu, XB Wu, Y Liang, N Li, X Hu, XD Lin… - Journal of Pain …, 2023 - Taylor & Francis
Background Neuropathic pain (NP) is a common and severe problem following spinal cord
injury (SCI). However, its relationship with functional outcome remains unclear. Methods A …

Extent of traumatic spinal cord injury is lesion level dependent and predictive of recovery: a multicenter neuroimaging study

S Schading-Sassenhausen, D Pfyffer… - Journal of …, 2024 - liebertpub.com
Assessing the extent of the intramedullary lesion after spinal cord injury (SCI) might help to
improve prognostication. However, because the neurological level of injury impacts the …

Recent developments and future avenues for human corticospinal neuroimaging

M Kaptan, D Pfyffer, CG Konstantopoulos… - Frontiers in Human …, 2024 - frontiersin.org
Non-invasive neuroimaging serves as a valuable tool for investigating the mechanisms
within the central nervous system (CNS) related to somatosensory and motor processing …