Abstract The interleukin 12 (IL-12) family is unique in having the only heterodimeric
cytokines, including IL-12, IL-23, IL-27 and IL-35. This feature endows these cytokines with a …

Approximately 5–10% of asthmatic patients worldwide suffer from severe asthma.
Experimental and clinical studies have demonstrated that IL-13 is an important cytokine in …

Allergic inflammation is due to a complex interplay between several inflammatory cells,
including mast cells, basophils, lymphocytes, dendritic cells, eosinophils, and sometimes …

Evidence accumulated over the last 5‐10 years indicates that glucocorticoids (GCs) inhibit
the production of interleukin (IL)‐12, interferon (IFN)‐γ, IFN‐α, and tumor necrosis factor …

Continuing Medical Education examination IL-13 is an immunoregulatory cytokine secreted
predominantly by activated TH2 cells. Over the past several years, it has become evident …

Cytokines mediate and control immune and inflammatory responses. Complex interactions
exist between cytokines, inflammation and the adaptive responses in maintaining …

Continuing Medical Education examination CONTINUING MEDICAL EDUCATION
ARTICLECredit can now be obtained, free for a limited time, by reading the following review …

BACKGROUND & AIMS:: Eosinophil infiltration into the esophagus occurs in a wide range of
diseases; however, the underlying pathophysiologic mechanisms involved are largely …

Background: IL-13 induces several characteristic features of asthma, including airway
eosinophilia, airway hyperresponsiveness, and mucus overproduction; however, the …

The neuroendocrine system affects the immune system through the neuroendocrine
humoral outflow via the pituitary, and through direct neuronal influences via the sympathetic …