The natural polymer chitosan is the second most abundant biopolymer on earth after chitin
and has been extensively explored for preparation of versatile drug delivery systems. The …

Marine-derived chitosan (CS) is a cationic polysaccharide widely studied for its bioactivity,
which is mostly attached to its primary amine groups. CS is able to neutralize reactive …

In the ever-evolving world of materials science, modifying natural polymers has garnered
significant attention across diverse industries, driven by their inherent availability and cost …

Bone defect is a serious problem for clinical orthopedics, and the construction of bone
implants with ideal size, shape, structure and demanded biofunctions, etc., is of great …

Medical device-associated infections pose a threat to healthcare budgets in both developed
and developing countries. Over the last decade, researchers have been looking for …

Osteomyelitis is a debilitating bone disorder characterized by an inflammatory process
involving the bone marrow, bone cortex, periosteum, and surrounding soft tissue, which can …

Biomanufacturing (BM) is a multidisciplinary area incorporating the characteristics of living
organisms and engineering principles to create valuable products for various sectors …

Introduction Discectomy and interbody fusion are widely used in the treatment of
intervertebral disc-related diseases. Among them, the interbody cage plays a significant role …

The coating of titanium with chitosan is a promising way to reduce the infection risk and to
modulate the inflammatory response of bone implants, but no effective coating procedure …

Constructing bio-based antibacterial composite multilayer coatings with sustained drug
release is important for reducing the infection risk of bone tissue repair. In this paper, a layer …