Role of nitric oxide in the pathogenesis of chronic pulmonary hypertension

V Hampl, J Herget - Physiological Reviews, 2000 - journals.physiology.org
Chronic pulmonary hypertension is a serious complication of a number of chronic lung and
heart diseases. In addition to vasoconstriction, its pathogenesis includes injury to the …

Mitochondria-Targeted Antioxidant Therapeutics for Traumatic Brain Injury

HR Modi, S Musyaju, M Ratcliffe, DA Shear… - Antioxidants, 2024 - mdpi.com
Traumatic brain injury (TBI) is a major global health problem that affects both civilian and
military populations worldwide. Post-injury acute, sub-acute, and chronic progression of …

Thiol compounds interact with nitric oxide in regulating heme oxygenase-1 induction in endothelial cells: involvement of superoxide and peroxynitrite anions

R Foresti, JE Clark, CJ Green, R Motterlini - Journal of Biological Chemistry, 1997 - ASBMB
Thiols are very important antioxidants that protect cells against oxidative insults. Recently, a
different and new physiological role has been defined for these compounds because of their …

Vascular smooth muscle relaxation mediated by nitric oxide donors: a comparison with acetylcholine, nitric oxide andnitroxyl ion

JC Wanstall, TK Jeffery, A Gambino… - British journal of …, 2001 - Wiley Online Library
Vasorelaxant properties of three nitric oxide (NO) donor drugs (glyceryl trinitrate, sodium
nitroprusside and spermine NONOate) in mouse aorta (phenylephrine pre‐contracted) were …

Melatonin attenuates pulmonary hypertension in chronically hypoxic rats

MW Hung, HM Yeung, CF Lau, AMS Poon… - International Journal of …, 2017 - mdpi.com
Chronic hypoxia induces pulmonary hypertension and vascular remodeling, which are
clinically relevant to patients with chronic obstructive pulmonary disease (COPD) associated …

On the distinction between nitroxyl and nitric oxide using nitronyl nitroxides

U Samuni, Y Samuni, S Goldstein - Journal of the American …, 2010 - ACS Publications
A better understanding of the origins of NO and HNO and their activities and biological
functions requires accurate methods for their detection and quantification. The unique …

Interaction between superoxide anion and nitric oxide in the regulation of vascular endothelial function

DW Laight, AV Kaw, MJ Carrier… - British journal of …, 1998 - Wiley Online Library
Nitric oxide (NO)‐mediated, endothelium‐dependent vasodilator function in rat aortic
smooth muscle was investigated in an in vitro model of endogenous vascular superoxide …

Recovery by ascorbate of impaired nitric oxide-dependent relaxation resulting from oxidant stress in rat aorta

S Dudgeon, DP Benson, A MacKenzie… - British journal of …, 1998 - ncbi.nlm.nih.gov
Recovery by ascorbate of impaired nitric oxide-dependent relaxation resulting from oxidant
stress in rat aorta Page 1 Recovery by ascorbate of impaired nitric oxide-dependent …

Potentiation of natriuretic peptide action by the β-adrenergic blocker carvedilol in hypertensive rats: a new antihypertensive mechanism

T Yoshimoto, M Naruse, A Tanabe, K Naruse… - …, 1998 - academic.oup.com
Abstract Treatment with a β-adrenergic blocker (β-blocker) in hypertension is associated
with increased plasma atrial natriuretic peptide (ANP) levels despite a decrease in cardiac …

Comparative study of the quercetin, ascorbic acid, glutathione and superoxide dismutase for nitric oxide protecting effects in mouse gastric fundus

PU Ertuğ, F Aydinoglu, OG Ozturk, E Singirik… - European journal of …, 2013 - Elsevier
The aim of this work was to compare the preventing capacity of quercetin with Cu/Zn
superoxide dismutase (Cu/Zn SOD), ascorbic acid and glutathione on nitric oxide (NO) …