Physiological roles of aquaporin-4 in brain

EA Nagelhus, OP Ottersen - Physiological reviews, 2013 - journals.physiology.org
Aquaporin-4 (AQP4) is one of the most abundant molecules in the brain and is particularly
prevalent in astrocytic membranes at the blood-brain and brain-liquor interfaces. While …

Regulation of AQP4 in the central nervous system

A Vandebroek, M Yasui - International journal of molecular sciences, 2020 - mdpi.com
Aquaporin-4 (AQP4) is the main water channel protein expressed in the central nervous
system (CNS). AQP4 is densely expressed in astrocyte end-feet, and is an important factor in …

Neuroimmunological implications of AQP4 in astrocytes

H Ikeshima-Kataoka - International journal of molecular sciences, 2016 - mdpi.com
The brain has high-order functions and is composed of several kinds of cells, such as
neurons and glial cells. It is becoming clear that many kinds of neurodegenerative diseases …

Regulation of brain aquaporins

M Zelenina - Neurochemistry international, 2010 - Elsevier
Three aquaporins are expressed in the brain. AQP4, the predominant brain water channel,
is expressed in astrocyte endfeet facing brain capillaries, perisynaptic spaces, and nodes of …

Structure–function analysis of plant aquaporin AtPIP2;1 gating by divalent cations and protons

L Verdoucq, A Grondin, C Maurel - Biochemical Journal, 2008 - portlandpress.com
Water channel proteins, AQPs (aquaporins), of the PIP (plasma membrane intrinsic protein)
subfamily, provide a means for fine and quick adjustments of the plant water status. A …

Molecular mechanisms of mercury-sensitive aquaporins

H Xie, S Ma, Y Zhao, H Zhou, Q Tong… - Journal of the …, 2022 - ACS Publications
Aquaporins are transmembrane channels that allow for the passive permeation of water and
other small molecules across biological membranes. Their channel activities are sensitive to …

Piscine aquaporins: an overview of recent advances

J Cerdà, RN Finn - Journal of Experimental Zoology Part A …, 2010 - Wiley Online Library
Aquaporins are a superfamily of integral membrane proteins that facilitate the rapid and yet
highly selective flux of water and other small solutes across biological membranes. Since …

Aquaporins: New players in breast cancer progression and treatment response

V Charlestin, D Fulkerson, CE Arias Matus… - Frontiers in …, 2022 - frontiersin.org
Aquaporins (AQPs) are a family of small transmembrane proteins that selectively transport
water and other small molecules and ions following an osmotic gradient across cell plasma …

Interstitial fibrosis restricts osmotic water transport in encapsulating peritoneal sclerosis

J Morelle, A Sow, N Hautem, C Bouzin… - Journal of the …, 2015 - journals.lww.com
Encapsulating peritoneal sclerosis (EPS) is a rare but severe complication of peritoneal
dialysis (PD) characterized by extensive fibrosis of the peritoneum. Changes in peritoneal …

Water permeability and characterization of aquaporin-11

K Yakata, K Tani, Y Fujiyoshi - Journal of Structural Biology, 2011 - Elsevier
The water permeability of aquaporin-11 (AQP11), which has a cysteine substituted for an
alanine at a highly conserved asparagine-proline-alanine (NPA) motif in the water channel …