The lentivirus human immunodeficiency virus (HIV) causes AIDS by interacting with a large
number of different cells in the body and escaping the host immune response against it. HIV …

The immunopathogenic mechanisms underlying human immunodeficiency virus (HIV)
disease are extremely complex; the disease process is multifactorial with multiple …

Macrophages have long been considered to contribute to HIV infection of the CNS; however,
a recent study has contradicted this early work and suggests that myeloid cells are not an in …

We examined the ability of chemokine receptors and related G protein–coupled receptors to
facilitate infection by primary, clinical HIV-1 isolates. CCR5, when expressed along with …

Guanylate binding proteins (GBPs) are an interferon (IFN)-inducible subfamily of guanosine
triphosphatases (GTPases) with well-established activity against intracellular bacteria and …

Autophagy is a cytoplasmic degradative pathway that can participate in biosynthetic
processes, as in the yeast Cvt pathway, but is more commonly known for its functions in …

Reactivation of human cytomegalovirus (HCMV) results in severe disease in AIDS patients
and immunocompromised patients receiving blood transfusions or organ or bone marrow …

This book grew out of a scientific review, originally published in Microbiological Reviews. It
has been updated and expanded-now citing more than 2100 references (100 pages of the …

Genome sequences of transmitted/founder (T/F) HIV-1 have been inferred by analyzing
single genome amplicons of acute infection plasma viral RNA in the context of a …

The replication of human immunodeficiency virus type 1 (HIV-1) in nondividing host cells
such as those of macrophage lineage is an important feature of AIDS pathogenesis. The …