Pyroptosis is a programmed cell death characterized by swift plasma membrane disruption
and subsequent release of cellular contents and pro-inflammatory mediators (cytokines) …

In the past decade, emerging viral outbreaks like SARS-CoV-2, Zika and Ebola have
presented major challenges to the global health system. Viruses are unique pathogens in …

Viruses are obligate intracellular pathogens as their replication depends on the metabolism
of the host cell. The induction of cellular suicide, known as programmed cell death (PCD) …

Staphylococcal endophthalmitis is one of the leading causes of blindness following ocular
surgery and trauma. Dysregulated inflammation during bacterial endophthalmitis causes …

Human cytomegalovirus (CMV) causes a common congenital infection leading to long-term
neurological impairments including brain, cochlear, and ocular pathology. Infection of …

Ocular infectious diseases are an important cause of potentially preventable vision loss and
blindness. In the following manuscript, we will review ocular immunology and the …

Retinal detachment (RD) is a sight-threatening condition that occurs in several retinal
diseases. Microglia that reside in retina are activated after RD and play a role in the death of …

With the appearance of the worldwide AIDS pandemic four decades ago came a number of
debilitating opportunistic infections in patients immunosuppressed by the pathogenic human …