Malignant ascites presents a considerable clinical challenge to the management of ovarian cancer, but also provides a wealth of opportunities for translational research. The …
DK Armstrong, RD Alvarez, JN Bakkum-Gamez… - Journal of the National …, 2021 - jnccn.org
Epithelial ovarian cancer is the leading cause of death from gynecologic cancer in the United States and is the country's fifth most common cause of cancer mortality in women. A …
E Pujade-Lauraine, JA Ledermann, F Selle… - The lancet …, 2017 - thelancet.com
Background Olaparib, a poly (ADP-ribose) polymerase (PARP) inhibitor, has previously shown efficacy in a phase 2 study when given in capsule formulation to all-comer patients …
TJ Perren, AM Swart, J Pfisterer… - … England Journal of …, 2011 - Mass Medical Soc
Background Angiogenesis plays a role in the biology of ovarian cancer. We examined the effect of bevacizumab, the vascular endothelial growth factor inhibitor, on survival in women …
A Du Bois, A Reuss, E Pujade‐Lauraine, P Harter… - Cancer, 2009 - Wiley Online Library
BACKGROUND: Primary surgery followed by platinum‐taxane based chemotherapy has been the standard therapy in advanced ovarian cancer. However, the prognostic role of …
SJ Chang, M Hodeib, J Chang, RE Bristow - Gynecologic oncology, 2013 - Elsevier
Objective To quantify the impact of complete cytoreduction to no gross residual disease on overall survival among patients with advanced-stage ovarian cancer treated during the …
N Katsumata, M Yasuda, F Takahashi, S Isonishi… - The Lancet, 2009 - thelancet.com
Background Paclitaxel and carboplatin given every 3 weeks is standard treatment for advanced ovarian carcinoma. Attempts to improve patient survival by including other drugs …
MA Bookman, MF Brady, WP McGuire… - Journal of clinical …, 2009 - ascopubs.org
Purpose To determine if incorporation of an additional cytotoxic agent improves overall survival (OS) and progression-free survival (PFS) for women with advanced-stage epithelial …
LC Hanker, S Loibl, N Burchardi, J Pfisterer, W Meier… - Annals of oncology, 2012 - Elsevier
Background Despite recent progress in the treatment of ovarian cancer, the majority of patients eventually relapse. There is little information on the effectiveness of chemotherapy …