Neurological and immunological signals constitute an extensive regulatory network in our
body that maintains physiology and homeostasis. The cholinergic system plays a significant …

It is surprising that the piriform cortex, when compared to the hippocampus, has been given
relatively little significance in human epilepsy. Like the hippocampus, it has a …

Epilepsy is characterized by recurrent synchronizations of neuronal activity, which are both a
cardinal clinical symptom and a debilitating phenomenon. Although the temporal dynamics …

Trimethyltin (TMT), an organotin compound with neurotoxicant effects selectively localised in
the limbic system and especially marked in the hippocampus, is considered a useful tool to …

Berberine hydrochloride is a plant alkaloid with versatile medicinal applications, yet it has
suffered from multiple limitations in its usage. Nonetheless, the acknowledged role of …

Neurodegenerative, neurological and psychiatric diseases are a group of pathologies with
huge social and economic impacts. Since brain disorders continue to be pathological …

NMDA and AMPA Receptors: Development and Status Epilepticus Page 1
PHYSIOLOGICAL RESEARCH • ISSN 0862-8408(print) • ISSN 1802-9973(online) © 2013 …

The blood-brain barrier (BBB) is dysfunctional in temporal lobe epilepsy (TLE). In this
regard, microvascular changes are likely present. The aim of this review is to provide an …

The maintenance of blood-brain barrier (BBB) integrity is essential for providing a suitable
environment for nervous tissue function. BBB disruption is involved in many central nervous …

Objective Epilepsy affects 60 million people worldwide. Despite the development of
antiepileptic drugs, up to 35% of patients are drug refractory with uncontrollable seizures …