Non-alcoholic fatty liver disease (NAFLD) is a quickly emerging global health problem
representing the most common chronic liver disease in the world. Atherosclerotic …

The prevalence of cardiovascular disease (CVD) is increasing over time. CVD is a
comorbidity in diabetes and contributes to premature death. Citrus flavonoids possess …

Atherosclerosis, the pathological basis of most cardiovascular disease (CVD), is closely
associated with cholesterol accumulation in the arterial intima. Excessive cholesterol is …

Epidemiological studies have suggested an inverse relationship between increased
consumption of fruits and reduced risk of chronic diseases, such as cardiovascular diseases …

In recent years, cardiovascular disease (CVD) has become more prevalent. Premature
death is a factor in CVD being associated with diabetes. According to epidemiological …

Flavonoids are common in the plant kingdom and many of them have shown a wide
spectrum of bioactive properties. Hesperetin (Hst), the aglycone form of hesperidin, is a …

Cholesterol is an essential component of cell membranes and helps to maintain their
structure and function. Abnormal cholesterol metabolism has been linked to the …

Hesperetin is a natural flavonoid with many biological activities. In view of hyperuricemia
treatment, the effects of hesperetin in vivo and in vitro, and the underlying mechanisms, were …

Abstract Sirtuin 1 (SIRT1) is a deacetylase enzyme that plays crucial roles in controlling
many cellular processes and its downregulation has been implicated in different metabolic …

Proprotein convertase subtilisin/kexin type 9 (PCSK9) is one of the key targets for
atherosclerosis drug development as its binding with low-density lipoprotein receptor leads …