Cell entry by SARS-CoV-2

R Peng, LA Wu, Q Wang, J Qi, GF Gao - Trends in biochemical sciences, 2021 - cell.com
Severe acute respiratory syndrome virus 2 (SARS-CoV-2) invades host cells by interacting
with receptors/coreceptors, as well as with other cofactors, via its spike (S) protein that …

Endothelium infection and dysregulation by SARS-CoV-2: evidence and caveats in COVID-19

I Bernard, D Limonta, LK Mahal, TC Hobman - Viruses, 2020 - mdpi.com
The ongoing pandemic of coronavirus disease 2019 (COVID-19) caused by the acute
respiratory syndrome-coronavirus-2 (SARS-CoV-2) poses a persistent threat to global public …

T cell response to SARS-CoV-2 infection in humans: A systematic review

M Shrotri, MCI van Schalkwyk, N Post, D Eddy… - PloS one, 2021 - journals.plos.org
Background Understanding the T cell response to SARS-CoV-2 is critical to vaccine
development, epidemiological surveillance and disease control strategies. This systematic …

Neutralisation of SARS-CoV-2 lineage P. 1 by antibodies elicited through natural SARS-CoV-2 infection or vaccination with an inactivated SARS-CoV-2 vaccine: an …

WM Souza, MR Amorim, R Sesti-Costa… - The Lancet …, 2021 - thelancet.com
Background Mutations accrued by SARS-CoV-2 lineage P. 1—first detected in Brazil in early
January, 2021—include amino acid changes in the receptor-binding domain of the viral …

[HTML][HTML] RETRACTED: SARS–CoV–2 Spike Impairs DNA Damage Repair and Inhibits V (D) J Recombination In Vitro

H Jiang, YF Mei - Viruses, 2021 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS–CoV–2) has led to the coronavirus
disease 2019 (COVID–19) pandemic, severely affecting public health and the global …

Human transferrin receptor can mediate SARS-CoV-2 infection

Z Liao, C Wang, X Tang, M Yang… - Proceedings of the …, 2024 - National Acad Sciences
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been
detected in almost all organs of coronavirus disease-19 patients, although some organs do …

An ACE2 microbody containing a single immunoglobulin Fc domain is a potent inhibitor of SARS-CoV-2

T Tada, C Fan, JS Chen, R Kaur, KA Stapleford… - Cell Reports, 2020 - cell.com
Soluble forms of angiotensin-converting enzyme 2 (ACE2) have recently been shown to
inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We report …

Will SARS-CoV-2 infection elicit long-lasting protective or sterilising immunity? Implications for vaccine strategies (2020)

DS Kim, S Rowland-Jones… - Frontiers in …, 2020 - frontiersin.org
In December 2019, an outbreak of a novel coronavirus (SARS-CoV-2) in Wuhan, China
resulted in the current COVID-19 global pandemic. The human immune system has not …

SARS–CoV-2 immuno-pathogenesis and potential for diverse vaccines and therapies: opportunities and challenges

AR McGill, R Khalil, R Dutta, R Green, M Howell… - Infectious Disease …, 2021 - mdpi.com
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is a novel coronavirus
that emerged from Wuhan, China in late 2019 causing coronavirus disease-19 (COVID-19) …

Low-Density Lipoprotein Receptor (LDLR) is involved in internalization of lentiviral particles pseudotyped with SARS-CoV-2 spike protein in ocular cells

S Uppal, O Postnikova, R Villasmil, IB Rogozin… - International Journal of …, 2023 - mdpi.com
Here, we present evidence that caveolae-mediated endocytosis using LDLR is the pathway
for SARS-CoV-2 virus internalization in the ocular cell line ARPE-19. Firstly, we found that …