Introduction: The search for an HIV cure involves important behavioural and social
processes that complement the domains of biomedicine. However, the field has yet to tap …

Thailand has the highest prevalence of HIV among countries in Asia but has also been a
pioneer in HIV prevention and treatment efforts in the region, reducing the incidence of new …

Introduction The question of what motivates people to participate in research is particularly
salient in the HIV field. While participation in HIV research was driven by survival in the …

Women remain underrepresented in HIV research. The AIDS Clinical Trials Group (ACTG)
5366 study was the first HIV cure-related trial conducted exclusively in women. Our …

Background The pursuit of a cure for HIV is a high priority for researchers, funding agencies,
governments and people living with HIV (PLWH). To date, over 250 biomedical studies …

Background A feature of HIV cure trials is the need to interrupt treatment to test the efficacy of
experimental interventions—a process known as analytical treatment interruptions (ATIs) …

As research into the development of an HIV cure gains prominence, assessing the
perspectives of stakeholders becomes imperative. It empowers stakeholders to determine …

HIV remission trials often require temporary stopping of antiretroviral therapy (ART)—an
approach called analytic treatment interruption (ATI). Trial designs resulting in viremia raise …

The AIDS Clinical Trials Group A5345 study (NCT03001128) included an intensively
monitored antiretroviral pause (IMAP), during which participants living with HIV temporarily …

Background The central nervous system (CNS) is a likely reservoir of human
immunodeficiency virus (HIV), vulnerable to viral rebound, inflammation, and clinical …