Over the past two decades, synergistic innovations in imaging technology have resulted in a
revolution in which a range of biomedical applications are now benefiting from fluorescence …

Cancer is a group of diseases responsible for the major causes of mortality and morbidity
among people of all ages. Even though medical sciences have made enormous growth …

For many solid tumors, surgical resection remains the gold standard and tumor-involved
margins are associated with poor clinical outcomes. Near-infrared (NIR) fluorescence …

Results: Both fluorescently labeled antibodies had similar pharmacodynamic properties and
minimal toxicities. Two infusion reactions occurred with cetuximab and none with …

In the past several decades, a number of novel fluorescence image-guided surgery (FGS)
contrast agents have been under development, with many in clinical translation and …

Background In the past decade, there has been a major drive towards clinical translation of
optical and, in particular, fluorescence imaging in surgery. In surgical oncology, radical …

Epidermal growth factor receptor (EGFR) and vascular endothelial growth factor receptor
(VEGFR) are two extensively studied membrane-bound receptor tyrosine kinase proteins …

Purpose: EGF receptor (EGFR) is highly overexpressed on several cancers and two targeted
anti-EGFR antibodies which differ by isotype are FDA-approved for clinical use. Cetuximab …

Antibody based positron emission tomography (immuno‐PET) imaging is of increasing
importance to visualize and characterize tumor lesions. Additionally, it can be used to …

Purpose: Comprehensive cervical lymphadenectomy can be associated with significant
morbidity and poor quality of life. This study evaluated the sensitivity and specificity of …