Multifunctional roles and pharmacological potential of β-sitosterol: Emerging evidence toward clinical applications

Z Khan, N Nath, A Rauf, TB Emran, S Mitra… - Chemico-Biological …, 2022 - Elsevier
Currently, available therapeutic medications are both costly as well as not entirely promising
in terms of potency. So, new candidates from natural resources are of research interest to …

Phytosterols: From preclinical evidence to potential clinical applications

B Salehi, C Quispe, J Sharifi-Rad… - Frontiers in …, 2021 - frontiersin.org
Phytosterols (PSs) are plant-originated steroids. Over 250 PSs have been isolated, and
each plant species contains a characteristic phytosterol composition. A wide number of …

[HTML][HTML] β-Sitosterol as a promising anticancer agent for chemoprevention and chemotherapy: mechanisms of action and future prospects

H Wang, Z Wang, Z Zhang, J Liu, L Hong - Advances in Nutrition, 2023 - Elsevier
Cancer is one of the primary causes of death worldwide, and its incidence continues to
increase yearly. Despite significant advances in research, the search for effective and …

Anticancer plants: A review of the active phytochemicals, applications in animal models, and regulatory aspects

T Khan, M Ali, A Khan, P Nisar, SA Jan, S Afridi… - Biomolecules, 2019 - mdpi.com
The rising burden of cancer worldwide calls for an alternative treatment solution. Herbal
medicine provides a very feasible alternative to western medicine against cancer. This …

Nutraceuticals and cancer: Potential for natural polyphenols

J Maiuolo, M Gliozzi, C Carresi, V Musolino… - Nutrients, 2021 - mdpi.com
Cancer is one of the leading causes of death globally, associated with multifactorial
pathophysiological components. In particular, genetic mutations, infection or inflammation …

[HTML][HTML] Plant sterols and plant stanols in the management of dyslipidaemia and prevention of cardiovascular disease

H Gylling, J Plat, S Turley, HN Ginsberg, L Ellegård… - Atherosclerosis, 2014 - Elsevier
Abstract Objective This EAS Consensus Panel critically appraised evidence relevant to the
benefit to risk relationship of functional foods with added plant sterols and/or plant stanols …

Molecular mechanism of β-sitosterol and its derivatives in tumor progression

X Bao, Y Zhang, H Zhang, L Xia - Frontiers in oncology, 2022 - frontiersin.org
β-Sitosterol (SIT), a white powdery organic substance with a molecular formula of C29H50O,
is one of the most abundant naturally occurring phytosterols in plants. With a chemical …

[HTML][HTML] Health aspects of peanuts as an outcome of its chemical composition

R Bonku, J Yu - Food Science and Human Wellness, 2020 - Elsevier
Peanut is an energy dense food item and it contains a substantial amount of fat, proteins,
carbohydrate, both fat soluble and water soluble vitamins, minerals and phytochemicals …

Dietary phytochemicals in cancer prevention and therapy: a complementary approach with promising perspectives

M González-Vallinas, M González-Castejón… - Nutrition …, 2013 - academic.oup.com
The population is aging. Over the coming years, the incidence of age-related chronic
diseases such as cancer is expected to continue to increase. Phytochemicals, which are non …

[HTML][HTML] Self-renewing monolayer of primary colonic or rectal epithelial cells

Y Wang, M DiSalvo, DB Gunasekara, J Dutton… - Cellular and molecular …, 2017 - Elsevier
Background & Aims Three-dimensional organoid culture has fundamentally changed the in
vitro study of intestinal biology enabling novel assays; however, its use is limited because of …