In healthy subjects and patients with hematological diseases, platelet populations can be
distinguished with different response spectra in hemostatic and vascular processes. These …

Background The water-soluble tomato extract, Fruitflow® is a dietary antiplatelet which can
be used to lower platelet aggregability in primary preventative settings. We carried out a pilot …

Acute myeloid leukemia (AML) patients carrying Fms-like tyrosine kinase 3-internal tandem
duplication (FLT3-ITD) mutations often face a poor prognosis. While some FLT3 inhibitors …

Platelet count represents a useful tool in clinical practice to discriminate individuals at higher
risk of bleeding. Less obvious is the role of platelet count variability within the normal range …

Background Myelodysplastic syndromes (MDSs) are a very heterogeneous group of myeloid
disorders with high prevalence and risk of developing acute myeloid leukemia. The more …

Introduction Smoking represents a major cardiovascular risk factor, due to the induction of
oxidative stress and low‐grade, continuous, inflammation that contribute to promote …

Background and aims Platelet count (PLT) is a predictor of metabolic and inflammation-
related disorders. Platelets can release prochemerin, which acts as a link between …

(1) Background: In a previous study, we found that two phenotypes related to platelet
reactivity, measured with the PFA-100 system, were highly heritable. The aim of the present …

Background Breast cancer (BC) is the most common and prominent deadly disease among
women. Predicting BC survival mainly relies on TNM staging, molecular profiling and …

Objective To determine whether mean platelet volume (MPV) and selected single nucleotide
polymorphisms (SNPs) that have been associated with MPV in genome-wide association …