TP53 is universally recognized as a pivotal protein in cell-cycle fate and apoptotic induction
and, unsurprisingly, it is one of the most commonly hijacked control mechanisms in cancer …

Normal protein‐protein interactions (normPPIs) occur with high fidelity to regulate almost
every physiological process. In cancer, this highly organised and precisely regulated …

Mitogen‐activated protein kinase (MAPK) signaling plays a significant role in reactive
oxygen species (ROS) production. The authors have previously shown that Brahma‐related …

Plant-based proteins are emerging at the forefront of functional food trends, as well as
sustainable components for various environmentally friendly and sustainable polymeric …

Background Nonalcoholic fatty liver disease (NAFLD) is a liver metabolic syndrome and still
lacks effective treatments because the molecular mechanism underlying the development of …

Motivation As cancer genomics initiatives move toward comprehensive identification of
genetic alterations in cancer, attention is now turning to understanding how interactions …

Here ginsenoside Rg1 was used to synthesise Rg1 carbon nanodots via a one-step
hydrothermal method. The surface of the Rg1 carbon nanodots is rich in hydrophilic …

Genetic aberrations driving pro-oncogenic and pro-metastatic activity remain an elusive
target in the quest of precision oncology. To identify such drivers, we use an animal model of …

Abstract Background African American women experience a twofold higher incidence of
triple-negative breast cancer (TNBC) and are 40% more likely to die from breast cancer than …

RNA sequencing and genetic data support spleen tyrosine kinase (SYK) and high affinity
immunoglobulin epsilon receptor subunit gamma (FCER1G) as putative targets to be …