2H/4H-Chromenes—A versatile biologically attractive Scaffold
2H/4H-chromene (2H/4H-ch) is an important class of heterocyclic compounds with versatile
biological profiles, a simple structure, and mild adverse effects. Researchers discovered …
biological profiles, a simple structure, and mild adverse effects. Researchers discovered …
The Chromenopyridine Scaffold: A Privileged Platform in Drug Design
F Pedroso de Lima, M Costa, A Sousa, MF Proença - Molecules, 2024 - mdpi.com
The chromenopyridine scaffold represents an important class of heterocyclic compounds
exhibiting a broad spectrum of biological properties. This review describes novel and …
exhibiting a broad spectrum of biological properties. This review describes novel and …
Advances in the greener synthesis of chromopyrimidine derivatives by a multicomponent tandem oxidation process
P Ghamari Kargar, G Bagherzade - Scientific Reports, 2023 - nature.com
A hydrophilic cobalt/copper heterogeneous bimetallic catalyst named mTEG-CS-Co/Cu-
Schiff-base/IL was successfully synthesized from chitosan polysaccharide. The new catalyst …
Schiff-base/IL was successfully synthesized from chitosan polysaccharide. The new catalyst …
Mechanochemical synthesis of azo-linked 2-amino-4H-chromene derivatives using Fe3O4@ SiO2@ KIT-6-NH2@ Schiff-base complex nanoparticles
M Nikpassand, A Keyhani, LZ Fekri… - Journal of Molecular …, 2022 - Elsevier
An efficient, solvent-free, and environmentally benign route via mechanochemical means is
described for the synthesis of azo-linked 2-amino-4H-chromene derivatives. The four …
described for the synthesis of azo-linked 2-amino-4H-chromene derivatives. The four …
Identification of 1, 3, 4-oxadiazoles as tubulin-targeted anticancer agents: a combined field-based 3D-QSAR, pharmacophore model-based virtual screening …
Cancer is one of the most prominent causes of death worldwide and tubulin is a crucial
protein of cytoskeleton that maintains essential cellular functions including cell division as …
protein of cytoskeleton that maintains essential cellular functions including cell division as …
Synthesis, characterization, anti-proliferative properties and DNA binding of benzochromene derivatives: Increased Bax/Bcl-2 ratio and caspase-dependent apoptosis …
MH Ahagh, G Dehghan, M Mehdipour… - Bioorganic …, 2019 - Elsevier
Amino-1-aryl-1H-benzo [f] chromene-2-carbonitrile derivatives were synthesized from three-
component reaction of arylaldehyde, malononitrile and 2-naphthol in the presence of 1, 4 …
component reaction of arylaldehyde, malononitrile and 2-naphthol in the presence of 1, 4 …
Synthesis of 1, 4-dihydropyrano [2, 3-c] pyrazole derivatives and exploring molecular and cytotoxic properties based on DFT and molecular docking studies
One-pot multicomponent reaction of ethyl 3-oxobutanoate or ethyl 3-oxo-3-
phenylpropanoate, hydrazine hydrate, malononitrile, various aldehydes in ethanolic …
phenylpropanoate, hydrazine hydrate, malononitrile, various aldehydes in ethanolic …
Insights into microwave assisted synthesis of spiro-chromeno [2, 3-d] pyrimidines using PEG-OSO3H catalyst: DFT study and their antiproliferative activity
Herein, we established an environmentally benign green approach for the synthesis of new
spirochromeno [2, 3-d] pyrimidines. PEG-4000-OSO 3 H catalysed microwave-assisted …
spirochromeno [2, 3-d] pyrimidines. PEG-4000-OSO 3 H catalysed microwave-assisted …
Synthesis, anticancer evaluation and molecular docking studies of new heterocycles linked to sulfonamide moiety as novel human topoisomerase types I and II …
AH Halawa, WE Elgammal, SM Hassan, AH Hassan… - Bioorganic …, 2020 - Elsevier
A series of heterocyclic compounds with a sulfonamide moiety were synthesized from
reaction of enaminone 4 with active methylene compounds, glycine derivatives, 1, 4 …
reaction of enaminone 4 with active methylene compounds, glycine derivatives, 1, 4 …
First example of Azo-Sulfa conjugated chromene moieties: Synthesis, characterization, antimicrobial assessment, docking simulation as potent class I histone …
This report presents the development of a novel and primary model of sulfonamide
compounds encompassing a chromene azo motif with the intent of becoming applicable for …
compounds encompassing a chromene azo motif with the intent of becoming applicable for …