Stroke, a neurological disease, is one of the leading causes of death worldwide, resulting in
long-term disability in most survivors. Annual stroke costs in the United States alone were …

Acute intracerebral hemorrhage (ICH) is a devastating type of stroke worldwide. Neuronal
destruction involved in the brain damage process caused by ICH includes a primary injury …

Microglial and astrocyte activation and related cytokine secretion play key roles in
secondary brain injury following intracerebral hemorrhage (ICH). We assessed the role of …

Background: Intracerebral hemorrhage (ICH) is a fatal subtype of stroke that lacks effective
therapy. Blood-brain barrier (BBB) damage is a hallmark of ICH-induced brain injury that …

In the past decades, hydrogen sulfide (H 2 S) has been considered as an important signal
molecule with a wide range of physiological functions. Therefore, disease treatment …

Background Intracerebral hemorrhage (ICH) is a condition associated with high morbidity
and mortality, and glia-mediated inflammation is a major contributor to neurological deficits …

Disruption of the blood-brain barrier (BBB) and the subsequent formation of brain edema is
the most severe consequence of intracerebral hemorrhage (ICH), leading to drastic …

The crosstalk between reactive astrocytes and infiltrated immune cells plays a critical role in
maintaining blood-brain barrier (BBB) integrity. However, how astrocytes interact with …

Recent investigations have revealed that oxidative stress can lead to neuronal damage and
disrupt mitochondrial and endoplasmic reticulum functions after intracerebral hemorrhage …

Stroke is one of the most common diseases that leads to brain injury and mortality in
patients, and intracerebral hemorrhage (ICH) is the most devastating subtype of stroke …