[图书][B] Targeted delivery of pesticides using biodegradable polymeric nanoparticles

A De, R Bose, A Kumar, S Mozumdar - 2014 - Springer
Pesticides have revolutionized life on this planet; however, they have also proven to be toxic
for human health and environment. Indeed, the extent and severity of the toxicity was …

Formulation of sodium valproate nanospanlastics as a promising approach for drug repurposing in the treatment of androgenic alopecia

FA Badria, HA Fayed, AK Ibraheem, AF State… - Pharmaceutics, 2020 - mdpi.com
Sodium valproate (SV) is an antiepileptic drug that is widely used in the treatment of different
seizure disorders. The topical SV has a hair regenerative potential through activating the …

Valproate intercalated in layered double hydroxides: synthesis, characterization, release kinetics and biocompatibility studies

NA Lopez, MC Crescitelli, CV Luengo, M Sánchez… - Ceramics …, 2024 - Elsevier
Layered double hydroxides (LDHs) are biocompatible materials with excellent anion
exchange properties, making them suitable for use as drug carriers by incorporating the …

Design and optimization of sustained-release divalproex sodium tablets with response surface methodology

F Monajjemzadeh, H Hamishehkar, P Zakeri-Milani… - AAPS …, 2013 - Springer
Response surface methodology is defined as a collection of mathematical and statistical
methods that are used to develop, improve, or optimize a product or process. In the present …

[HTML][HTML] Development and characterization of hygroscopicity-controlled sustain release formulation of divalproex sodium

S Adhikari, U Budhathoki, P Thapa - Turkish Journal of …, 2022 - ncbi.nlm.nih.gov
Objectives: Divalproex sodium (DS), being a hygroscopic drug, requires low humidity during
product manufacturing. This study aims to develop a hygroscopicity controlled sustained …

Preparation, optimization and in vitro–in vivo evaluation of Shunxin sustained release granules

Y Dou, X Li, Y Shi, J Zhang, Y Yuan, M Zhou, X Wei… - Chinese Medicine, 2019 - Springer
Background Shunxinzufang decoction is tutors, empirical formula and has been used in
Chinese patients of HFpEF for several years. The aim of this study was to make into …

[PDF][PDF] Development and validation of RP-HPLC method for estimation of valproic acid in dissolution study of its formulation

M Karde, H Pawar, R Geevarghese… - Int J Pharmacy Pharm Sci …, 2012 - academia.edu
ABSTRACT A simple, precise and reproducible reverse phase, isocratic high performance
liquid chromatographic (HPLC) method was developed and validated for the quantitative …

[PDF][PDF] STATISTICAL OPTIMIZATION AND ASSESSMENT OF DIVALPROEX SODIUM EXTENDED RELEASE TABLET

RK Gunda, NSK Jujjuru, A Vijayalakshmi… - Indian Drugs, 2023 - researchgate.net
The purpose of the current experimental research was to optimize the quantities of
macromolecules such as Eudragit L/100-55 and HPMC-K-100M for the development of …

Novel polymeric prodrugs of valproic acid as anti-epilepsy drugs: Synthesis, characterization and in-vitro evaluation

SN Amiryaghoubi, M Babazadeh - Tropical Journal of Pharmaceutical …, 2015 - ajol.info
Purpose: To synthesize and evaluate, in-vitro, novel polymeric prodrugs of valproic acid
(VPA) for antiepileptic activity. Methods: Homopolymer of 4-chloromethyl styrene (CMS) and …

Antiepileptika v pevných lékových formách s prodlouženým uvolňováním

P Němeček - 2017 - dk.upce.cz
Tato práce je literární rešerší na téma" Antiepileptika v pevných lékových formách s
prodlouženým uvolňováním". V úvodu jsou definovány typy epilepsie a druhy epileptických …