T cells and natural killer (NK) cells have complementary roles in tumor immunity, and dual T
cell and NK cell attack thus offers opportunities to deepen the impact of immunotherapy …

NK1. 1 and its human homolog CD161 are expressed on NK cells, subsets of CD4+ and
CD8+ T cells, and NKT cells. While the expression of NK1. 1 is thought to be inhibitory to NK …

T cells are critical effectors of cancer immunotherapies, but little is known about their gene
expression programs in diffuse gliomas. Here, we leverage single-cell RNA sequencing …

The success of immune checkpoint therapy in cancer has changed our way of thinking,
promoting the design of future cancer treatments that places the immune system at the …

Natural killer (NK) lymphocytes are an integral component of the innate immune system and
represent important effector cells in cancer immunotherapy, particularly in the control of …

Natural killer (NK) cells play a pivotal role in the immune system, especially in the
recognition and clearance of cancer cells and infected cells. Their effector function is …

Background Expression of killer cell lectin-like receptor B1 (KLRB1), the gene encoding the
cell surface molecule CD161, is associated with favorable prognosis in many cancers …

Signaling by the human C-type lectin-like receptor, natural killer (NK) cell inhibitory receptor
NKR-P1, has a critical role in many immune-related diseases and cancer. C-type lectin-like …

ABSTRACT NK cells have shown promise in therapy of hematological cancers, in particular
against acute myeloid leukemia. In contrast, the more NK cell-resistant acute lymphoblastic …

Prostate cancer is the most common type of cancer diagnosed and the second leading
cause of cancer-related death in American men. Natural Killer (NK) cells are the first line of …