Genomic insight into the diversity of Glaesserella parasuis isolates from 19 countries

X Gong, Q Cui, W Zhang, Y Shi, P Zhang, C Zhang… - Msphere, 2024 - journals.asm.org
Glaesserella parasuis is a commensal bacterial organism found in the upper respiratory tract
of healthy pigs and the etiological agent of Glässer's disease, which causes severe …

Metaproteomic analysis of nasopharyngeal SWAB samples to identify microbial peptides in COVID-19 patients

S Bihani, A Gupta, S Mehta… - Journal of Proteome …, 2023 - ACS Publications
During the COVID-19 pandemic, impaired immunity and medical interventions resulted in
cases of secondary infections. The clinical difficulties and dangers associated with …

Proof of concept for prevention of natural colonization by oral needle-free administration of a microparticle vaccine

R Frandoloso, S Chaudhuri, GCP Frandoloso… - Frontiers in …, 2020 - frontiersin.org
There has been substantial interest in the development of needle-free vaccine
administration that has led to a variety of approaches for delivery through the skin for …

Design of a multi-epitope vaccine against Haemophilus parasuis based on pan-genome and immunoinformatics approaches

M Pang, T Tu, Y Wang, P Zhang, M Ren… - Frontiers in Veterinary …, 2022 - frontiersin.org
Background Glässer's disease, caused by Haemophilus parasuis (HPS), is responsible for
economic losses in the pig industry worldwide. However, the existing commercial vaccines …

Molecular characterization of Glaesserella parasuis strains isolated from North America, Europe and Asia by serotyping PCR and LS-PCR

N Macedo, M Gottschalk, K Strutzberg-Minder… - Veterinary …, 2021 - Springer
Glaesserella parasuis strains were characterized by serotyping PCR, vtaA virulence marker
Leader Sequence (LS)-PCR, clinical significance, and geographic region. Overall, the …

Insights from targeting transferrin receptors to develop vaccines for pathogens of humans and food production animals

NF Ewasechko, S Chaudhuri… - Frontiers in Cellular and …, 2023 - frontiersin.org
While developing vaccines targeting surface transferrin receptor proteins in Gram-negative
pathogens of humans and food production animals, the common features derived from their …

Virulence assessment of four Glaesserella parasuis strains isolated in Liaoning province of China

P Yan, YC Jia, XL Zhang, YY Zhou, Y Guo… - Research in Veterinary …, 2023 - Elsevier
Glaesserella parasuis (G. parasuis) is a part of the normal upper respiratory microbiota of
healthy swine. In many studies, the serovars 1, 4, 5, and 12 of G. parasuis are considered to …

[HTML][HTML] TbpBY167A-based vaccine can protect pigs against glässer's disease triggered by glaesserella parasuis SV7 expressing TbpB cluster I

SR Prigol, R Klein, S Chaudhuri, GP Frandoloso… - Pathogens, 2022 - ncbi.nlm.nih.gov
Glaesserella parasuis is the etiological agent of Glässer's disease (GD), one of the most
important diseases afflicting pigs in the nursery phase. We analyzed the genetic and …

Main Causes of Death in Piglets from Different Brazilian Nursery Farms Based on Clinical, Microbiological, and Pathological Aspects

JCO Menegatt, FF Perosa, AH Gris, MM Piva… - Animals, 2023 - mdpi.com
Simple Summary Mortality within the nursery pig herd constitutes a pivotal factor contributing
to economic losses and concurrently serves as a valuable indicator of production efficiency …

TbpBY167A-based vaccine is safe in pregnant sows and induces high titers of maternal derived antibodies that reduce Glaesserella parasuis colonization in piglets

D Dellagostin, RL Klein, I Giacobbo, JA Guizzo… - Veterinary …, 2023 - Elsevier
Glässer's disease is one of the main diseases affecting young piglets, particularly during the
nursery phase, that can significantly impact pork production. Vaccination of sows has the …