Revealing the inhibition mechanism of RNA-dependent RNA polymerase (RdRp) of SARS-CoV-2 by remdesivir and nucleotide analogues: A molecular dynamics …

PD Wakchaure, S Ghosh… - The Journal of Physical …, 2020 - ACS Publications
Antiviral drug therapy against SARS-CoV-2 is not yet established and posing a serious
global health issue. Remdesivir is the first antiviral compound approved by the US FDA for …

Antiangiogenesis activity of Indonesian local black garlic (Allium Sativum 'Solo): Experiments and bibliometric analysis

R Arianingrum, N Aznam, S Atun… - Indonesian Journal of …, 2023 - ejournal.kjpupi.id
Cancer is still one of the leading causes of death in the world. Angiogenesis is the formation
of new blood vessels, which plays a vital role in the growth of cancer cells. As a result …

[HTML][HTML] Two novel compounds, ergosterol and ergosta-5, 8-dien-3-ol, from Termitomyces heimii Natarajan demonstrate promising anti-hepatocarcinoma activity

R Ray, S Saha, S Paul - Journal of Traditional Chinese Medical Sciences, 2022 - Elsevier
Background Mushroom-derived components have immense potential to become a safe
alternative in identifying lead anti-cancer molecules. Termitomyces heimii Natarajan (T …

Active phytochemicals of Pueraria tuberosa for DPP-IV inhibition: in silico and experimental approach

S Srivastava, P Shree, YB Tripathi - Journal of Diabetes & Metabolic …, 2017 - Springer
Background We had earlier reported that the extract of Pueraria tuberosa significantly
inhibits DPP-IV enzyme, resulting in glucose tolerance response in rats. In this study, we …

The potential mechanism of Bupleurum against anxiety was predicted by network pharmacology study and molecular docking

HB Wu, YG Xiao, JS Chen, ZK Qiu - Metabolic Brain Disease, 2022 - Springer
Bupleurum chinense DC.(Chaihu) is a traditional Chinese medicine (TCM) used in the
treatment of anxiety. But the anxiolytic mechanisms of bupleurum are still unclear. Therefore …

[HTML][HTML] Incretin hormones receptor signaling plays the key role in antidiabetic potential of PTY-2 against STZ-induced pancreatitis

S Srivastava, P Shree, H Pandey, YB Tripathi - Biomedicine & …, 2018 - Elsevier
Aims Incretin therapy is one of the most potential approaches in the treatment of diabetes. In
contrast to markedly available drugs, the herbal incretin modulators have lesser side effects …

[PDF][PDF] In silico investigation of black tea components on α-amylase, α-glucosidase and lipase

S Mohapatra, A Prasad, F Haque, S Ray… - Journal of Applied …, 2015 - japsonline.com
Black tea is one of the most widely consumed beverages in the world and traditionally
known for its antidiabetic and antiobesity property. However, the underlying mechanisms of …

[PDF][PDF] In Vitro screening and in silico docking analysis identifies two novel compound lecanoric acid and atranorin from Parmotrema tinctorum, exhibiting potent anti …

S Saha, R Ray, S Paul - Biointerface Res Appl Chem, 2023 - biointerfaceresearch.com
Lichens are a good repository of bio-active compounds with different pharmacological
properties; therefore, in our article, we aim to screen the antiproliferative potential of three …

Anti-oxidant, anti-apoptotic, anti-hypoxic and anti-inflammatory conditions induced by PTY-2 against STZ-induced stress in islets

S Srivastava, H Pandey, SK Singh, YB Tripathi - Bioscience trends, 2019 - jstage.jst.go.jp
The earlier assessment of Pueraria tuberosa (PT) has shown anti-diabetic effects through
enhancing incretin action and DPP-IV (Dipeptidyl peptidase-IV) inhibition. The aim of this …

Imatinib exhibit synergistic pleiotropy in the prevention of colorectal cancer by suppressing proinflammatory, cell survival and angiogenic signaling

DK Dhiman, SN Sanyal, V Vaish - Cellular Signalling, 2020 - Elsevier
Recent global incidences and mortality rates have placed colorectal cancer (CRC) at third
and second positions, respectively, among both sexes of all ages. Resistance during …