There has been a steep increase in allergic and autoimmune diseases, reaching epidemic
proportions and now affecting more than one billion people worldwide. These diseases are …

In the era of the rapid development of cancer immunotherapy, there is a high level of interest
in the application of cell-released small vesicles that stimulate the immune system. As cell …

Unconventional T cells include γδ T cells, invariant Natural Killer T cells (iNKT) cells and
Mucosal Associated Invariant T (MAIT) cells, which are distinguished from conventional T …

Obesity and ageing predispose to numerous, yet overlapping chronic diseases. For
example, metabolic abnormalities, including insulin resistance (IR) and type 2 diabetes …

In recent times, the emergence of viral infections, including the SARS-CoV-2 virus, the
monkeypox virus, and, most recently, the Langya virus, has highlighted the devastating …

Background BRCA1-associated protein (BRAP) is a critical gene that regulates inflammation-
related signaling pathway and affects patients' prognosis in esophageal squamous cell …

Immune cells and immune molecules in the intestinal mucosa participate in innate and
adaptive immunity to maintain local and systematic homeostasis. With aging, intestinal …

Background The intestinal barrier encompasses physical and immunological components
that act to compartmentalize luminal contents, such as bacteria and endotoxins, from the …

Abstract Background and Objective Diabetes accelerates inflammaging in various tissue
with an increase in senescent cell burden and senescence‐associated secretory phenotype …

The study of free-living animal populations is necessary to understand life history trade-offs
associated with immune investment. To investigate the role of life history strategies in …