Brain temperature, as an independent therapeutic target variable, has received increasingly
intense clinical attention. To date, brain hypothermia represents the most potent …

Background: Mild to moderate hypothermia (32–35 C) is the first treatment with proven
efficacy for postischemic neurological injury. In recent years important insights have been …

Severe excessive autonomic overactivity occurs in a subgroup of people surviving acquired
brain injury, the majority of whom show paroxysmal sympathetic and motor overactivity …

Brain temperature (BT) is a crucial physiological parameter used to monitor cerebral status.
Physical activities and traumatic brain injuries (TBI) can affect BT; therefore, non-invasive BT …

Objective: Elevated temperature results in worse outcome in experimental models of
cerebral ischemia and brain trauma. In critically ill neurologic and neurosurgical patients …

The regulation of brain temperature is largely dependent on the metabolic activity of brain
tissue and remains complex. In intensive care clinical practice, the continuous monitoring of …

Electronic patches, based on various mechanisms, allow continuous and noninvasive
monitoring of biomolecules on the skin surface. However, to date, such devices are unable …

Our understanding of how capillary blood flow and oxygen distribute across cortical layers to
meet the local metabolic demand is incomplete. We addressed this question by using two …

Objective: Therapeutic hypothermia has been used to attenuate the effects of traumatic brain
injuries. However, the required degree of hypothermia, length of its use, and its timing are …

Therapeutic hypothermia involves the controlled reduction of core temperature to attenuate
the secondary organ damage which occurs following a primary injury. Clinicians have been …