Calcium pumps of the plasma membrane (also known as plasma membrane Ca 2+-
ATPases or PMCAs) are responsible for the expulsion of Ca 2+ from the cytosol of all …

The Ca2+ ATP ases of the plasma membrane (PMCA pumps) export Ca2+ from all
eukaryotic cells. In mammals they are the products of four separate genes. PMCA types 1 …

Ca2+ in neurons is vital to processes such as neurotransmission, neurotoxicity, synaptic
development, and gene expression. Disruption of Ca2+ homeostasis occurs in brain aging …

Calcium ions (Ca2+) are prominent cell signaling effectors that regulate a wide variety of
cellular processes. Among the different players in Ca2+ homeostasis, primary active Ca2+ …

The expression at the protein level of plasma membrane calcium pump (PMCA) isoforms in
rat brain was detected by new antibodies that distinguished the four gene products and their …

In this review, I summarize the present knowledge of the structural and functional properties
of the mammalian plasma membrane calcium pump (PMCA). It is outlined how the cellular …

The epitope location and specificity of monoclonal antibodies JA9, 5F10 and JA3, raised
against the human plasma membrane Ca2+ pump (hPMCA), were analysed by using …

The plasma membrane calcium ATPases are critical components in the regulation of cellular
calcium homeostasis and signaling. In mammals, there are 4 Pmca genes, and information …

Ca2+ extrusion by high‐affinity plasma membrane calcium ATPases (PMCAs) is a principal
mechanism for the clearance of Ca2+ from the cytosol. The PMCA family consists of four …

Calcium in mammalian neurons is essential for developmental processes, neurotransmitter
release, apoptosis, and signal transduction. Incorrectly processed Ca2+ signal is well …