Long noncoding RNAs in cell-fate programming and reprogramming

RA Flynn, HY Chang - Cell stem cell, 2014 - cell.com
In recent years, long noncoding RNAs (lncRNAs) have emerged as an important class of
regulators of gene expression. lncRNAs exhibit several distinctive features that confer …

Non-coding RNAs as direct and indirect modulators of epigenetic regulation

VJ Peschansky, C Wahlestedt - Epigenetics, 2014 - Taylor & Francis
Epigenetic regulation of gene expression is an increasingly well-understood concept that
explains much of the contribution of an organism's environment and experience to its …

From discovery to function: the expanding roles of long noncoding RNAs in physiology and disease

M Sun, WL Kraus - Endocrine reviews, 2015 - academic.oup.com
Long noncoding RNAs (lncRNAs) are a relatively poorly understood class of RNAs with little
or no coding capacity transcribed from a set of incompletely annotated genes. They have …

[HTML][HTML] The long noncoding RNA RMST interacts with SOX2 to regulate neurogenesis

SY Ng, GK Bogu, BS Soh, LW Stanton - Molecular cell, 2013 - cell.com
Long noncoding RNAs (lncRNAs) are abundant in the mammalian transcriptome, and many
are specifically expressed in the brain. We have identified a group of lncRNAs, including …

H19 induces abdominal aortic aneurysm development and progression

DY Li, A Busch, H Jin, E Chernogubova, J Pelisek… - Circulation, 2018 - Am Heart Assoc
Background: Long noncoding RNAs have emerged as critical molecular regulators in
various biological processes and diseases. Here we sought to identify and functionally …

Long non-coding RNAs as emerging regulators of differentiation, development, and disease

BK Dey, AC Mueller, A Dutta - Transcription, 2014 - Taylor & Francis
A significant portion of the mammalian genome encodes numerous transcripts that are not
translated into proteins, termed long non-coding RNAs. Initial studies identifying long non …

[HTML][HTML] bHLH transcription factors in neural development, disease, and reprogramming

DJ Dennis, S Han, C Schuurmans - Brain research, 2019 - Elsevier
The formation of functional neural circuits in the vertebrate central nervous system (CNS)
requires that appropriate numbers of the correct types of neuronal and glial cells are …

Long noncoding RNAs in development and disease of the central nervous system

SY Ng, L Lin, BS Soh, LW Stanton - Trends in Genetics, 2013 - cell.com
The central nervous system (CNS) is a complex biological system composed of numerous
cell types working in concert. The intricate development and functioning of this highly …

Long non-coding RNA in health and disease

PG Maass, FC Luft, S Bähring - Journal of molecular medicine, 2014 - Springer
Long non-coding RNAs (lncRNAs) interact with the nuclear architecture and are involved in
fundamental biological mechanisms, such as imprinting, histone-code regulation, gene …

[图书][B] RNA, the epicenter of genetic information

J Mattick, P Amaral - 2023 - library.oapen.org
The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …