Metabolic engineering and synthetic biology strategies for producing high-value natural pigments in Microalgae

K Cao, Y Cui, F Sun, H Zhang, J Fan, B Ge, Y Cao… - Biotechnology …, 2023 - Elsevier
Microalgae are microorganisms capable of producing bioactive compounds using
photosynthesis. Microalgae contain a variety of high value-added natural pigments such as …

The role of astaxanthin as a nutraceutical in health and age-related conditions

G Bjørklund, A Gasmi, L Lenchyk, M Shanaida, S Zafar… - Molecules, 2022 - mdpi.com
The current review provides an up-to-date analysis of scientific data on astaxanthin (ASX)
sources and experimental studies on its health benefits as a potent antioxidant in the aging …

De novo synthesis of astaxanthin: From organisms to genes

N Fang, C Wang, X Liu, X Zhao, Y Liu, X Liu… - Trends in Food Science …, 2019 - Elsevier
Background Astaxanthin is a ketocarotenoid with stronger antioxidant activity than vitamin E
and coenzyme Q10, and with pharmacological effects against cancer, cardiovascular …

Molecular approaches to enhance astaxanthin biosynthesis; future outlook: engineering of transcription factors in Haematococcus pluvialis

SI Kayani, S -Rahman, Q Shen, Y Cui… - Critical Reviews in …, 2024 - Taylor & Francis
Microalgae are the preferred species for producing astaxanthin because they pose a low
toxicity risk than chemical synthesis. Astaxanthin has multiple health benefits and is being …

Astaxanthin overproduction of Phaffia rhodozyma PR106 under titanium dioxide stress by transcriptomics and metabolic regulation analysis

J Zhang, Q Li, Y Lu, X Guan, J Liu, N Xu, C Cai… - Bioresource …, 2021 - Elsevier
In this study, astaxanthin yield of Phaffia rhodozyma PR106 increased significantly under
titanium dioxide (TiO 2) stress, and the yield of lycopene and β-carotene also increased …