Trying to conceive and being pregnant is an emotional period for those involved. In the
majority of patients suffering from inflammatory bowel disease, maintenance therapy is …

Beside cytotoxic drugs, other drugs can impact men's fertility through various mechanisms.
Via the modification of the hypothalamic–pituitary–gonadal axis hormones or by non …

Fistulating Crohn's disease (CD) comprises fistulae arising in the perianal area, together
with those communicating between the intestine and other organs or the abdominal wall …

Tumor necrosis factor-alpha (TNF-α) is a multifunctional Th1 cytokine and one of the most
important inflammatory cytokines. In pregnancy, TNF-α influences hormone synthesis …

Rheumatic diseases in women of childbearing years may necessitate drug treatment during
a pregnancy, to control maternal disease activity and to ensure a successful pregnancy …

Women with inflammatory bowel disease (IBD) have similar rates of fertility to the general
population, but have an increased rate of adverse pregnancy outcomes compared with the …

Inflammatory bowel diseases (IBD) typically affect patients in their reproductive years. It has
been shown that reproductive issues are of key concern to IBD patients, 1 especially …

There is limited evidence relating to the impact of disease modifying anti-rheumatic drugs
(DMARDs) upon male fertility and peri-conception paternal exposure in men with rheumatic …

BACKGROUND Information regarding the possible influence of immunosuppressive drugs
on male sexual function and reproductive outcomes is scarce. Men diagnosed with immune …

Biologic therapies have revolutionized treatment outcomes for patients with inflammatory
arthritis. However, there remains a concern regarding their safety during conception …