Reactions between N-acyliminium ions and nucleophiles–also described as
amidoalkylation or Mannich type condensations–have been frequently utilized to introduce …

Conclusions The first part of this review clearly demonstrates the diversity and power of
asymmetric domino reactions based on the use of chiral auxiliaries in the field of synthetic …

1. Introduction....................................................................... 11512 2. Chemical resolution of chiral
synthetic intermediates.................................... 11515 2.1. By recrystallization of diastereomeric …

In comparison to all carbon [4+ 2] cycloadditions, Diesl‐Alder reactions are still in their
infancy. The last four decades, however, have seen intensive research in this area. The …

The enzyme 5α-reductase (5αR) catalyses the reduction of testosterone (T) into the more
potent androgen dihydrotestosterone (DHT). The abnormal production of DHT is associated …

3aα-H-4α-(3′-Propionic acid)-5α-hydroxy-7aβ-methylhexahydro-1-indanone-δ-lactone
(sitolactone, or HIL) and 3aα-H-4α-(3′-propionic acid)-7aβ-methylhexahydro-1, 5 …

A benzannulation sequence featuring [6π+ 4π] cycloaddition of (η6-thiepin 1, 1-dioxide)
tricarbonylchromium (0) complexes with highly substituted dienes followed by Ramberg …

A Mannich–Michael combo: An efficient and highly enantioselective cascade process by H‐
bonding catalysis for the synthesis of functionalized tetrahydroquinolines has been …

The synthesis and biological evaluation of a series of novel, selective inhibitors of
isoenzyme 1 of human 5α-reductase (5αR)(EC 1.3. 99.5) are reported. The inhibitors are 4a …

The synthesis and the inhibition potency of octahydro-and decahydrobenzo [c] quinolizin-3-
one derivatives 3–7, as new non-steroidal selective inhibitors of human enzyme 5α …