Suppression of antitumor immune responses is one of the main mechanisms by which tumor
cells escape from destruction by the immune system. Myeloid-derived suppressor cells …

Pancreatic cancer is a devastating disease and ranks as the third most common cause of
cancer-related death. Like many cancers, there has been increased interest in the role of the …

Pathological conditions including cancers lead to accumulation of a morphological mixture
of highly immunosuppressive cells termed as myeloid-derived suppressor cells (MDSC) …

Increased levels of myeloid cells, especially myeloid-derived suppressor cells (MDSCs),
have been reported to correlate with bad prognosis and reduced survival in cancer patients …

Cutaneous melanoma is a relatively common, potentially lethal skin tumor of increasing
incidence, with a propensity to affect relatively young patients, and a highly variable survival …

MDSCs (myeloid-derived suppressor cells) are crucial for immune system evasion in cancer.
They accumulate in peripheral blood and tumor microenvironment, suppressing immune …

Immune evasion is a recently defined hallmark of cancer, and immunotherapeutic
approaches that stimulate an immune response to tumours are gaining recognition …

The pancreatic ductal adenocarcinoma (PDAC) microenvironment plays a critical role in the
antitumor immune response. 2-arachidonoylglycerol (2-AG) exhibits a direct antitumor effect …

Cancer research has seen unprecedented advances over the past several years, with
tremendous insights gained into mechanisms of response and resistance to cancer therapy …

Objectives This study aimed to determine the systemic and local proportions, focal
localization, and characteristics of polymorphonuclear myeloid-derived suppressor cells …