The discovery in 2006 that loss-of-function mutations in the filaggrin gene (FLG) cause
ichthyosis vulgaris and can predispose to atopic dermatitis (AD) galvanized the dermatology …

The discovery, in 2006, that loss-of-function mutations in the filaggrin (FLG) gene are the
cause of ichthyosis vulgaris—the most common disorder of keratinization—and also a strong …

Background: Atopic dermatitis is a common inflammatory skin disorder that affects up to 15–
20% of the population and is characterized by recurrent eczematous lesions with intense …

Ichthyosis vulgaris is caused by loss‐of‐function mutations in the filaggrin gene (FLG) and is
characterized clinically by xerosis, scaling, keratosis pilaris, palmar and plantar …

Background Atopic dermatitis (AD) is a prevalent disease with significant impact on physical
health and quality of life. Staphylococcus aureus has been directly correlated to disease …

BACKGROUND: Enhanced apoptosis of keratinocytes is the main cause of eczema and
spongiosis in patients with the common inflammatory skin disease atopic dermatitis (AD) …

Biomarkers associated with the development of comorbidities in atopic dermatitis (AD)
patients have been reported, but have not yet been systematically reviewed. Seven …

Background Atopic dermatitis (AD) and loss‐of‐function mutations in the filaggrin gene
(FLG) are both associated with chronic irritant contact dermatitis (ICD). As FLG mutations …

Introduction: Atopic dermatitis (AD) is a common inflammatory skin disease regulated by
genetic and environmental factors. Both skin barrier defects and aberrant immune …

Atopic dermatitis (AD) is a common inflammatory skin disease with underlying defects in
epidermal function and immune responses. In this study, we used microarray analysis to …