Medicinal plants are a rich source of natural products used to treat many diseases; therefore,
they are the basis for a new drug discovery. Plants are capable of generating different …

Covering: 1991 to November 2011 A growing body of evidence indicates that the
Pestalotiopsis genus represents a huge and largely untapped resource of natural products …

Taxol®(generic name Paclitaxel) is a chemotherapeutic drug, effective against head, neck,
breast, lung, bladder, ovary, and cervix cancers. Rising demands in chemotherapy and …

Taxol, a phyto-extracted diterpenoid, is the most commercially needed drug in cancer
chemotherapy. In spite of the microbial production of taxol being successful and prospective …

Species within the fungal genus Pestalotiopsis have become a topic of research in many
microbial-chemical and pharmacological laboratories because they contain structurally …

Fatty acid and their amide derivatives are natural self-defense agents in plants. They have
been observed to be broadly bioactive against a variety of disease agents. The mechanism …

Fungal endophytes have marked a significant impact on drug discovery reducing the burden
and dependency on plants. The vast diversity of Pestalotiopsis sp. has emerged as …

Traditional application of plant in folk medicine is a base for discovery of new active
chemical substances. In the second half of 20th century, significant antitumor activity of …

Six new cyclopentenyl esters, avellaneine A–F (1–4, 7, 8), two new cyclopentyl esters,
avellaneine G, H (9, 10), along with two known cyclopentenyl esters were obtained from …

While taxol yields of fungi from non-animal sources are still low, whether Pestalotiopsis
hainanensis isolated from the scurf of a dermatitic giant panda, Ailuropoda melanoleuca …