A review of near infrared spectroscopy and chemometrics in pharmaceutical technologies

Y Roggo, P Chalus, L Maurer, C Lema-Martinez… - … of pharmaceutical and …, 2007 - Elsevier
Near-infrared spectroscopy (NIRS) is a fast and non-destructive analytical method.
Associated with chemometrics, it becomes a powerful tool for the pharmaceutical industry …

Near infrared and Raman spectroscopy for the in-process monitoring of pharmaceutical production processes

T De Beer, A Burggraeve, M Fonteyne… - International journal of …, 2011 - Elsevier
Within the Process Analytical Technology (PAT) framework, it is of utmost importance to
obtain critical process and formulation information during pharmaceutical processing …

Near infrared spectroscopy: fundamentals, practical aspects and analytical applications

C Pasquini - Journal of the Brazilian chemical society, 2003 - SciELO Brasil
This paper intends to review the basic theory of Near Infrared (NIR) Spectroscopy and its
applications in the field of Analytical Science. It is addressed to the reader who does not …

Near-infrared spectroscopy and imaging: basic principles and pharmaceutical applications

G Reich - Advanced drug delivery reviews, 2005 - Elsevier
Near-infrared (NIR) spectroscopy and imaging are fast and nondestructive analytical
techniques that provide chemical and physical information of virtually any matrix. In …

Near-infrared spectroscopy applications in pharmaceutical analysis

J Luypaert, DL Massart, Y Vander Heyden - Talanta, 2007 - Elsevier
Near-infrared (NIR) spectroscopy is a fast and non-destructive analytical technique that
offers many advantages for a broad range of industrial applications. In this work, we …

Process analytical technology tools for monitoring pharmaceutical unit operations: a control strategy for continuous process verification

EJ Kim, JH Kim, MS Kim, SH Jeong, DH Choi - Pharmaceutics, 2021 - mdpi.com
Various frameworks and methods, such as quality by design (QbD), real time release test
(RTRT), and continuous process verification (CPV), have been introduced to improve drug …

Recent progress in continuous manufacturing of oral solid dosage forms

V Vanhoorne, C Vervaet - International Journal of Pharmaceutics, 2020 - Elsevier
Continuous drug product manufacturing is slowly being implemented in the pharmaceutical
industry. Although the benefits related to the quality and cost of continuous manufacturing …

Pharmaceutical applications of vibrational chemical imaging and chemometrics: a review

C Gendrin, Y Roggo, C Collet - Journal of pharmaceutical and biomedical …, 2008 - Elsevier
The emergence of chemical imaging (CI) has gifted spectroscopy an additional dimension.
Chemical imaging systems complement chemical identification by acquiring spatially …

A review of in-line and on-line measurement techniques to monitor industrial mixing processes

AL Bowler, S Bakalis, NJ Watson - Chemical Engineering Research and …, 2020 - Elsevier
Mixing is a ubiquitous operation in process engineering. It is not only used for combining
materials, but also for promoting heat and mass transfer, increasing aeration, suspending …

Lactose characteristics and the generation of the aerosol

G Pilcer, N Wauthoz, K Amighi - Advanced drug delivery reviews, 2012 - Elsevier
The delivery efficiency of dry-powder products for inhalation is dependent upon the drug
formulation, the inhaler device, and the inhalation technique. Dry powder formulations are …