Andrographolide, a natural anti-inflammatory agent: An Update

X Li, W Yuan, J Wu, J Zhen, Q Sun, M Yu - Frontiers in pharmacology, 2022 - frontiersin.org
Botanicals have attracted much attention in the field of anti-inflammatory due to their good
pharmacological activity and efficacy. Andrographis paniculata is a natural plant ingredient …

Potential Plant-Based New Antiplasmodial Agent Used in Papua Island, Indonesia

RB Indradi, M Muhaimin, MI Barliana, A Khatib - Plants, 2023 - mdpi.com
Resistance to antimalarial medicine remains a threat to the global effort for malaria
eradication. The World Health Organization recently reported that artemisinin partial …

Dual anti-malarial and GSK3β-mediated cytokine-modulating activities of quercetin are requisite of its potential as a plant-derived therapeutic in malaria

AH Ali, S Sudi, N Shi-Jing, WRM Hassan, R Basir… - Pharmaceuticals, 2021 - mdpi.com
Although death in malaria is attributed to cerebrovascular blockage and anaemia,
overwhelming cytokine production can contribute to the severity of the disease. Therefore …

A review on the molecular basis underlying the protective effects of Andrographis paniculata and andrographolide against myocardial injury

SK Wong, KY Chin, S Ima-Nirwana - Drug Design, Development …, 2021 - Taylor & Francis
Andrographolide is the major compound found in the medicinal plant, Andrographis
paniculata (Burm. f.) Nees, which accounts for its medicinal properties. Both the plant extract …

[HTML][HTML] Scoping insight on antiviral drugs against COVID-19

AS Ali, IM Ibrahim, AS Burzangi, RH Ghoneim… - Arabian Journal of …, 2021 - Elsevier
Background COVID-19 is an ongoing viral pandemic produced by SARS-CoV-2. In light of in
vitro efficacy, several medications were repurposed for its management. During clinical use …

Site-Selective Synthesis of C-17 Ester Derivatives of Natural Andrographolide for Evaluation as a Potential Anticancer Agent

G Kumar, S Thapa, JA Tali, D Singh, BK Sharma… - ACS …, 2023 - ACS Publications
A library of 57 compounds of natural andrographolide was designed, synthesized, and
screened for in vitro studies against four human cancer cell lines: A594, PC-3, MCF-7, and …

Andrographolide derivative Andro-III modulates neuroinflammation and attenuates neuropathological changes of Alzheimer's disease via GSK-3β/NF-κB/CREB …

M Hu, M Zheng, C Wang, Q Li, J Li, X Zhou… - European Journal of …, 2024 - Elsevier
Andrographolide has anti-inflammatory and neuroprotective effects, making it a potential
therapeutic option for Alzheimer's disease (AD). Our research group optimized its structure …

Ethnobotanical survey on bitter tea in Taiwan

J Chao, TY Chen, LH Pao, JS Deng… - Frontiers in …, 2022 - frontiersin.org
Ethnopharmacological evidence: In Taiwan, herbal tea is considered a traditional medicine
and has been consumed for hundreds of years. In contrast to regular tea, herbal teas are …

Synthesis and anti-plasmodial activity of isoandrographolide acetals

N Tamang, SK Mavileti, M Yadav, S Nanduri, D Sahal… - Chemical Papers, 2023 - Springer
Isoandrographolide (2) and its nineteen acetals (3a–3o, 4, 5 and 6a–6b) of which fifteen are
new were synthesized and characterized using 1H-NMR, 13C-NMR, mass spectrometry …

[HTML][HTML] A critical review of Andrographis paniculata

X Chen, J Ren, J Yang, Z Zhu, R Chen… - Medicinal Plant …, 2023 - maxapress.com
Andrographis paniculata, a traditional medicinal plant, is widely used to treat various
disorders. According to traditional Chinese medicine (TCM) theory, it is intensely bitter in …