A review on recent developments for biomolecule separation at analytical scale using microfluidic devices

KKR Tetala, MA Vijayalakshmi - Analytica chimica acta, 2016 - Elsevier
Microfluidic devices with their inherent advantages like the ability to handle 10− 9 to 10− 18
L volume, multiplexing of microchannels, rapid analysis and on-chip detection are proving to …

Recent advances in micro-/nanostructure array integrated microfluidic devices for efficient separation of circulating tumor cells

H Kang, Y Xiong, L Ma, T Yang, X Xu - RSC advances, 2022 - pubs.rsc.org
Circulating tumor cells (CTCs) released from the primary tumor to peripheral blood are
promising targets for liquid biopsies. Their biological information is vital for early cancer …

A filter paper-based microdevice for low-cost, rapid, and automated DNA extraction and amplification from diverse sample types

W Gan, B Zhuang, P Zhang, J Han, CX Li, P Liu - Lab on a Chip, 2014 - pubs.rsc.org
A plastic microfluidic device that integrates a filter disc as a DNA capture phase was
successfully developed for low-cost, rapid and automated DNA extraction and PCR …

UV activation of polymeric high aspect ratio microstructures: ramifications in antibody surface loading for circulating tumor cell selection

JM Jackson, MA Witek, ML Hupert, C Brady… - Lab on a Chip, 2014 - pubs.rsc.org
The need to activate thermoplastic surfaces using robust and efficient methods has been
driven by the fact that replication techniques can be used to produce microfluidic devices in …

Maximizing interfacial bonding strength between PDMS and PMMA substrates for manufacturing hybrid microfluidic devices withstanding extremely high flow rate and …

TNA Vo, PC Chen - Sensors and Actuators A: Physical, 2022 - Elsevier
Polydimethylsiloxane (PDMS) and polymethylmethacrylate (PMMA) are widely used in
microfluidics, due to their excellent biocompatibility, high optical transparency, and ease of …

Development of chip-compatible sample preparation for diagnosis of infectious diseases

M Ritzi-Lehnert - Expert review of molecular diagnostics, 2012 - Taylor & Francis
Diagnosis of infectious diseases in primary care is predominantly based on medical history
and physical examination, as conventional laboratory investigations are often associated …

Molecular separation by using active and passive microfluidic chip designs: a comprehensive review

A Ebrahimi, K Icoz, R Didarian, CH Shih… - Advanced Materials …, 2024 - Wiley Online Library
Separation and identification of molecules and biomolecules such as nucleic acids, proteins,
and polysaccharides from complex fluids are known to be important due to unmet needs in …

Miniaturized bead-beating device to automate full DNA sample preparation processes for Gram-positive bacteria

KY Hwang, SH Kwon, SO Jung, HK Lim, WJ Jung… - Lab on a Chip, 2011 - pubs.rsc.org
We have developed a miniaturized bead-beating device to automate nucleic acids
extraction from Gram-positive bacteria for molecular diagnostics. The microfluidic device …

[PDF][PDF] Recent development and application of solid phase extraction materials

Z Li, B Yu, H Cong, H Yuan, Q Peng - Rev. Adv. Mater. Sci, 2017 - ipme.ru
Recently, the solid phase extraction technology has received considerable attention
considering serious environmental problems and much more contaminants present in the …

Design and fabrication of microfluidics system integrated with temperature actuated microvalve

A Zahra, R Scipinotti, D Caputo, A Nascetti… - Sensors and Actuators A …, 2015 - Elsevier
This paper presents the design and fabrication of a microfluidic structure on a glass
substrate for fluid handling in lab-on-chip systems. A polydimethilsiloxane microfluidic …