The role of the thyroid axis in fish

CK Deal, H Volkoff - Frontiers in endocrinology, 2020 - frontiersin.org
In all vertebrates, the thyroid axis is an endocrine feedback system that affects growth,
differentiation, and reproduction, by sensing and translating central and peripheral signals to …

Thyroid hormone plays an important role in cardiac function: from bench to bedside

H Yamakawa, TS Kato, JY Noh, S Yuasa… - Frontiers in …, 2021 - frontiersin.org
Thyroid hormones (THs) are synthesized in the thyroid gland, and they circulate in the blood
to regulate cells, tissues, and organs in the body. In particular, they exert several effects on …

Genomic and non-genomic mechanisms of action of thyroid hormones and their catabolite 3, 5-diiodo-l-thyronine in mammals

M Giammanco, CM Di Liegro, G Schiera… - International Journal of …, 2020 - mdpi.com
Since the realization that the cellular homologs of a gene found in the retrovirus that
contributes to erythroblastosis in birds (v-erbA), ie the proto-oncogene c-erbA encodes the …

Cancer-associated thrombosis: risk factors, molecular mechanisms, future management

MS Hamza, SA Mousa - Clinical and Applied Thrombosis …, 2020 - journals.sagepub.com
Venous thromboembolism (VTE) is a major health problem in patients with cancer. Cancer
augments thrombosis and causes cancer-associated thrombosis (CAT) and vice versa …

Survival-associated metabolic genes in human papillomavirus-positive head and neck cancers

MA Prusinkiewicz, SF Gameiro, F Ghasemi, MJ Dodge… - Cancers, 2020 - mdpi.com
Human papillomavirus (HPV) causes an increasing number of head and neck squamous
cell carcinomas (HNSCCs). Altered metabolism contributes to patient prognosis, but the …

Co-targeting tumor angiogenesis and immunosuppressive tumor microenvironment: A perspective in ethnopharmacology

J Zhou, L Wang, C Peng, F Peng - Frontiers in Pharmacology, 2022 - frontiersin.org
Tumor angiogenesis is one of the most important processes of cancer deterioration via
nurturing an immunosuppressive tumor environment (TME). Targeting tumor angiogenesis …

Thyroid hormones act as modulators of inflammation through their nuclear receptors

M Lasa, C Contreras-Jurado - Frontiers in endocrinology, 2022 - frontiersin.org
Reciprocal crosstalk between endocrine and immune systems has been well-documented
both in physiological and pathological conditions, although the connection between the …

Comparative Analysis of Transcriptome Profiles Reveals Distinct and Organ-Dependent Genomic and Nongenomic Actions of Thyroid Hormone in Xenopus tropicalis …

S Wang, Y Shibata, Y Tanizaki, H Zhang, W Yan, L Fu… - Thyroid, 2023 - liebertpub.com
Background: Thyroid hormone (triiodothyronine [T3]) is essential for development and organ
metabolism in all vertebrates. T3 has both genomic and nongenomic effects on target cells …

Thyroid hormone facilitates in vitro decidualization of human endometrial stromal cells via thyroid hormone receptors

M Kakita-Kobayashi, H Murata, A Nishigaki… - …, 2020 - academic.oup.com
Endometrial stromal cells differentiate into decidual cells through the process of
decidualization. This differentiation is critical for embryo implantation and the successful …

Molecular diagnostic review of diffuse large B-Cell lymphoma and its tumor microenvironment

R Ta, D Yang, C Hirt, T Drago, R Flavin - Diagnostics, 2022 - mdpi.com
Diffuse large B-cell lymphoma (DLBCL) is the most common non-Hodgkin lymphoma. It is a
clinically and morphologically heterogeneous entity that has continued to resist complete …