Drug release from in situ forming implants and advances in release testing

X Wang, DJ Burgess - Advanced Drug Delivery Reviews, 2021 - Elsevier
In situ forming implants, defined as liquid formulations that generate solid or semisolid
depots following administration, have shown a range of advantages in drug delivery. This …

Drug carriers for the delivery of therapeutic peptides

AW Du, MH Stenzel - Biomacromolecules, 2014 - ACS Publications
Peptides take on an increasingly important role as therapeutics in areas including diabetes,
oncology, and metabolic, cardiovascular, and infectious diseases. In addition, many …

[图书][B] Therapeutic peptides and proteins: formulation, processing, and delivery systems

AK Banga - 2005 - taylorfrancis.com
Upon publication of the first edition of Therapeutic Peptides and Proteins ten years ago there
were only 19 biotechology medicines on the market. Currently there are more than 100, with …

Drug-releasing implants: current progress, challenges and perspectives

A Santos, MS Aw, M Bariana, T Kumeria… - Journal of Materials …, 2014 - pubs.rsc.org
The need for more efficient drug delivery strategies to treat resilient diseases and the rise of
micro and nanotechnology have led to the development of more sophisticated drug …

Recent progress in preparation and agricultural application of microcapsules

T Li, D Teng, R Mao, Y Hao, X Wang… - Journal of Biomedical …, 2019 - Wiley Online Library
Recent advances in life science technology have prompted the need to develop
microcapsule delivery systems that can encapsulate many different functional or active …

Comparison of lipid liquid crystal formulation and Vivitrol® for sustained release of Naltrexone: in vitro evaluation and pharmacokinetics in rats

H Kamali, M Karimi, M Abbaspour, A Nadim… - International Journal of …, 2022 - Elsevier
Camurus' FluidCrystal® injection depot is a lipid liquid crystal (LLC) phase formation-based
method, comprising of glycerol dioleate (GDO) and soy phosphatidylcholine (SPC), together …

Optimization of injectable PLGA in-situ forming implants of anti-psychotic risperidone via Box-Behnken Design

TM Ibrahim, NA El-Megrab, HM El-Nahas - Journal of Drug Delivery …, 2020 - Elsevier
The current study aims to develop in-situ forming implants (ISFI) of anti-psychotic risperidone
to customize schizophrenia therapy. Non-adherence to treatment is the most prevalent …

Size and morphology controlling of PLGA microparticles produced by electro hydrodynamic atomization

M Jafari‐Nodoushan, J Barzin… - Polymers for Advanced …, 2015 - Wiley Online Library
Among the various methods used to produce microparticles, electrospraying is becoming
increasingly popular, and it has the advantage of control over the size, shape and …

An in-situ forming implant formulation of naltrexone with minimum initial burst release using mixture of PLGA copolymers and ethyl heptanoate as an additive: In-vitro …

H Kamali, E Khodaverdi, F Hadizadeh… - Journal of Drug Delivery …, 2018 - Elsevier
An in-situ forming implant formulation of naltrexone (NTX) was achieved based on a
minimum initial burst release of NTX in the in-vitro release medium using a Box-Behnken …

Optimization and in vitro evaluation of injectable sustained-release of levothyroxine using PLGA-PEG-PLGA

H Kamali, E Khodaverdi, E Kaffash, AS Saffari… - Journal of …, 2021 - Springer
Purpose In situ-forming gels (semi-solid state)(ISFGs) are widely used as sustained drug
delivery, but they show a high burst release as well. The purpose of the current study is to …