[HTML][HTML] Gallium containing bioactive materials: A review of anticancer, antibacterial, and osteogenic properties

F Kurtuldu, N Mutlu, AR Boccaccini, D Galusek - Bioactive Materials, 2022 - Elsevier
The incorporation of gallium into bioactive materials has been reported to enhance
osteogenesis, to influence blood clotting, and to induce anti-cancer and anti-bacterial …

Adult stem cells for bone regeneration and repair

MR Iaquinta, E Mazzoni, I Bononi… - Frontiers in cell and …, 2019 - frontiersin.org
The regeneration of bone fractures, resulting from trauma, osteoporosis or tumors, is a major
problem in our super-aging society. Bone regeneration is one of the main topics of concern …

Design strategies and biomimetic approaches for calcium phosphate scaffolds in bone tissue regeneration

F Pupilli, A Ruffini, M Dapporto, M Tavoni, A Tampieri… - Biomimetics, 2022 - mdpi.com
Bone is a complex biologic tissue, which is extremely relevant for various physiological
functions, in addition to movement, organ protection, and weight bearing. The repair of …

Gallium-enabled bactericidal medicine

Y Liu, F Yang, Z Pan, Z Fu, X Jiang, Z Cao, J Li… - Materials Today, 2023 - Elsevier
Metallic materials have been used as antibacterial agents since antiquity. Gallium (Ga), an
abiogenic metal, has shown pharmaceutical effects in developing unconventional …

Enhancement of the biological and mechanical performances of sintered hydroxyapatite by multiple ions doping

S Sprio, M Dapporto, L Preti, E Mazzoni… - Frontiers in …, 2020 - frontiersin.org
In the present work, hydroxyapatite (HA) nanoparticles doped with Mg2+, Sr2+, and Zn2+
ions are developed by wet neutralization method and then sintered at 1,250° C to obtain …

Synergic role of zinc and gallium doping in hydroxyapatite nanoparticles to improve osteogenesis and antibacterial activity

M Shokri, M Kharaziha, HA Tafti, MB Eslaminejad… - Biomaterials …, 2022 - Elsevier
Recently, postoperative bone infections have been one of the most crucial challenges for
surgeons. This study aims to synergistically promote antibacterial and osteoconductive …

Influence of the biological medium on the properties of magnesium doped hydroxyapatite composite coatings

D Predoi, SC Ciobanu, SL Iconaru, MV Predoi - Coatings, 2023 - mdpi.com
In this paper, the stability of magnesium-doped hydroxyapatite/chitosan (MHC) suspension
obtained with the sol-gel approach was evaluated using nondestructive ultrasound …

[HTML][HTML] Multi-doped apatite: Strontium, magnesium, gallium and zinc ions synergistically affect osteogenic stimulation in human mesenchymal cells important for bone …

M Vukomanovic, L Gazvoda, N Anicic, M Rubert… - Biomaterials …, 2022 - Elsevier
Functional calcium phosphate biomaterials can be designed as carriers of a balanced
mixture of biologically relevant ions able to target critical processes in bone regeneration …

[HTML][HTML] A novel antimicrobial strategy for bacterial infections: Gallium-based materials

F Shi, SS Ma, S Liu, R Xin, B Chen, W Ye… - Colloid and Interface …, 2023 - Elsevier
Bacterial infections remain a significant challenge in clinical medicine, and pervasive
bacterial contamination addressed is based on the rational use of biomedical antibacterial …

Gallium-Doped Hydroxyapatite Shows Antibacterial Activity against Pseudomonas aeruginosa without Affecting Cell Metabolic Activity

M Mosina, C Siverino, L Stipniece, A Sceglovs… - Journal of Functional …, 2023 - mdpi.com
Calcium phosphates (CaPs) have been used in bone regeneration for decades. Among the
described CaPs, synthetic hydroxyapatite (HAp) has a chemical composition similar to that …