Inflammation in hypertension
L Xiao, DG Harrison - Canadian Journal of Cardiology, 2020 - Elsevier
For more than 50 years, evidence has accumulated that inflammation contributes to the
pathogenesis of hypertension. Immune cells have been observed in vessels and kidneys of …
pathogenesis of hypertension. Immune cells have been observed in vessels and kidneys of …
Monocyte trafficking across the vessel wall
T Gerhardt, K Ley - Cardiovascular research, 2015 - academic.oup.com
Monocytes fundamentally contribute to immune surveillance and the inflammatory response
in immunoinflammatory diseases like atherosclerosis. Recruitment of these cells to the site …
in immunoinflammatory diseases like atherosclerosis. Recruitment of these cells to the site …
Bioinspired exosome-mimetic nanovesicles for targeted delivery of chemotherapeutics to malignant tumors
Exosomes, the endogenous nanocarriers that can deliver biological information between
cells, were recently introduced as new kind of drug delivery system. However, mammalian …
cells, were recently introduced as new kind of drug delivery system. However, mammalian …
Complement receptors and their role in leukocyte recruitment and phagocytosis
S Vandendriessche, S Cambier, P Proost… - Frontiers in Cell and …, 2021 - frontiersin.org
The complement system is deeply embedded in our physiology and immunity. Complement
activation generates a multitude of molecules that converge simultaneously on the …
activation generates a multitude of molecules that converge simultaneously on the …
Vascular macrophages in atherosclerosis
Atherosclerosis is the main pathological basis for the occurrence of most cardiovascular
diseases, the leading global health threat, and a great burden for society. It has been well …
diseases, the leading global health threat, and a great burden for society. It has been well …
Vascular cell adhesion molecule-1 expression and signaling during disease: regulation by reactive oxygen species and antioxidants
JM Cook-Mills, ME Marchese… - Antioxidants & redox …, 2011 - liebertpub.com
The endothelium is immunoregulatory in that inhibiting the function of vascular adhesion
molecules blocks leukocyte recruitment and thus tissue inflammation. The function of …
molecules blocks leukocyte recruitment and thus tissue inflammation. The function of …
Long-term impacts of preeclampsia on the cardiovascular system of mother and offspring
Preeclampsia is a pregnancy-specific complication that is associated with an increased
postpartum risk of cardiovascular disease (CVD) in both women and their offspring, although …
postpartum risk of cardiovascular disease (CVD) in both women and their offspring, although …
A major role for VCAM-1, but not ICAM-1, in early atherosclerosis
MI Cybulsky, K Iiyama, H Li, S Zhu… - The Journal of …, 2001 - Am Soc Clin Investig
VCAM-1 and ICAM-1 are endothelial adhesion molecules of the Ig gene superfamily that
may participate in atherogenesis by promoting monocyte accumulation in the arterial intima …
may participate in atherogenesis by promoting monocyte accumulation in the arterial intima …
Vascular adhesion molecules in atherosclerosis
Numerous reports document the role of vascular adhesion molecules in the development
and progression of atherosclerosis. Recent novel findings in the field of adhesion molecules …
and progression of atherosclerosis. Recent novel findings in the field of adhesion molecules …
Lack of interleukin-1β decreases the severity of atherosclerosis in ApoE-deficient mice
H Kirii, T Niwa, Y Yamada, H Wada… - … , and vascular biology, 2003 - Am Heart Assoc
Objective—Atherosclerosis is considered to be a chronic inflammatory disease and many
cytokines participate in the development of atherosclerosis. We focused on the role of …
cytokines participate in the development of atherosclerosis. We focused on the role of …