Alphavirus-based expression vectors: strategies and applications.
I Frolov, TA Hoffman, BM Prágai… - Proceedings of the …, 1996 - National Acad Sciences
Alphaviruses are positive-strand RNA viruses that can mediate efficient cytoplasmic gene
expression in insect and vertebrate cells. Through recombinant DNA technology, the …
expression in insect and vertebrate cells. Through recombinant DNA technology, the …
[HTML][HTML] Rab proteins
O Martinez, B Goud - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 1998 - Elsevier
Rab proteins form the largest branch of the Ras superfamily of GTPases. They are localized
to the cytoplasmic face of organelles and vesicles involved in the biosynthetic/secretory and …
to the cytoplasmic face of organelles and vesicles involved in the biosynthetic/secretory and …
Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis.
Small GTPases of the rab family control distinct steps of intracellular transport. The function
of their GTPase activity is not completely understood. To investigate the role of the …
of their GTPase activity is not completely understood. To investigate the role of the …
[HTML][HTML] Toward a comprehensive map of the effectors of rab GTPases
Summary The Rab GTPases recruit peripheral membrane proteins to intracellular
organelles. These Rab effectors typically mediate the motility of organelles and vesicles and …
organelles. These Rab effectors typically mediate the motility of organelles and vesicles and …
Rab 7: an important regulator of late endocytic membrane traffic.
Y Feng, B Press, A Wandinger-Ness - The Journal of cell biology, 1995 - rupress.org
Rab5 and rab7 proteins belong to a superfamily of small molecular weight GTPases known
to be associated with early and late endosomes, respectively. The rab5 protein plays an …
to be associated with early and late endosomes, respectively. The rab5 protein plays an …
A regulatory role for ARF6 in receptor-mediated endocytosis
Adenosine diphosphate-ribosylation factor 6 (ARF6), ARF6 mutants, and ARF1 were
transiently expressed in Chinese hamster ovary cells, and the effects on receptor-mediated …
transiently expressed in Chinese hamster ovary cells, and the effects on receptor-mediated …
[HTML][HTML] A Salmonella virulence protein that inhibits cellular trafficking
K Uchiya, MA Barbieri, K Funato, AH Shah… - The EMBO …, 1999 - embopress.org
Salmonella enterica requires a type III secretion system, designated Spi/Ssa, to survive and
proliferate within macrophages. The Spi/Ssa system is encoded within the SPI‐2 …
proliferate within macrophages. The Spi/Ssa system is encoded within the SPI‐2 …
Hepatitis C virus entry requires a critical postinternalization step and delivery to early endosomes via clathrin-coated vesicles
L Meertens, C Bertaux, T Dragic - Journal of virology, 2006 - Am Soc Microbiol
Hepatitis C virus (HCV) is a major human pathogen associated with life-threatening liver
disease. Entry into hepatocytes requires CD81 and a putative second receptor. In this study …
disease. Entry into hepatocytes requires CD81 and a putative second receptor. In this study …
An interferon-α-induced tethering mechanism inhibits HIV-1 and Ebola virus particle release but is counteracted by the HIV-1 Vpu protein
SJD Neil, V Sandrin, WI Sundquist, PD Bieniasz - Cell host & microbe, 2007 - cell.com
Type 1 interferon (IFN) inhibits the release of HIV-1 virus particles via poorly defined
mechanisms. Here, we show that IFNα induces retention of viral particles on the surface of …
mechanisms. Here, we show that IFNα induces retention of viral particles on the surface of …
HIV-1 Vpu promotes release and prevents endocytosis of nascent retrovirus particles from the plasma membrane
SJD Neil, SW Eastman, N Jouvenet… - PLoS …, 2006 - journals.plos.org
The human immunodeficiency virus (HIV) type-1 viral protein U (Vpu) protein enhances the
release of diverse retroviruses from human, but not monkey, cells and is thought to do so by …
release of diverse retroviruses from human, but not monkey, cells and is thought to do so by …