[HTML][HTML] Artemisinin-based combination therapy (ACT) and drug resistance molecular markers: A systematic review of clinical studies from two malaria endemic …

A Arya, LPK Foko, S Chaudhry, A Sharma… - International Journal for …, 2021 - Elsevier
Artemisinin-based combination therapies (ACT) are currently used as a first-line malaria
therapy in endemic countries worldwide. This systematic review aims at presenting the …

Geographical spread and structural basis of sulfadoxine-pyrimethamine drug-resistant malaria parasites

R Chaturvedi, J Chhibber-Goel, I Verma… - International Journal for …, 2021 - Elsevier
The global spread of sulfadoxine (Sdx, S) and pyrimethamine (Pyr, P) resistance is attributed
to increasing number of mutations in DHPS and DHFR enzymes encoded by malaria …

Declining efficacy of artesunate plus sulphadoxine-pyrimethamine in northeastern India

N Mishra, K Kaitholia, B Srivastava, NK Shah… - Malaria journal, 2014 - Springer
Background Anti-malarial drug resistance in Plasmodium falciparum in India has historically
travelled from northeast India along the Myanmar border. The treatment policy for P …

Malaria elimination in India and regional implications

K Wangdi, ML Gatton, GC Kelly, C Banwell… - The Lancet infectious …, 2016 - thelancet.com
The malaria situation in India is complex as a result of diverse socio-environmental
conditions. India contributes a substantial burden of malaria outside sub-Saharan Africa …

High prevalence of asymptomatic malaria in a tribal population in eastern India

S Ganguly, P Saha, SK Guha, A Biswas… - Journal of clinical …, 2013 - Am Soc Microbiol
Asymptomatic infection by Plasmodium falciparum is an important obstacle to eliminating
malaria. Asymptomatic carriers do not seek treatment for infection, and therefore they …

Prevalence of mutations linked to antimalarial resistance in Plasmodium falciparum from Chhattisgarh, Central India: A malaria elimination point of view

P Patel, PK Bharti, D Bansal, NA Ali, RK Raman… - Scientific reports, 2017 - nature.com
Antimalarial drug resistance is a major global challenge in malaria control and elimination.
Mutations in six different genes of Plasmodium falciparum (crt, mdr1, dhfr, dhps, ATPase6 …

[HTML][HTML] Meta-analysis on Plasmodium falciparum sulfadoxine-pyrimethamine resistance-conferring mutations in India identifies hot spots for genetic surveillance

A Sinha, S Kar, C Chauhan, CP Yadav, L Kori - International Journal of …, 2024 - Elsevier
Background India is on track to eliminate malaria by 2030 but emerging resistance to first-
line antimalarials is a recognised threat. Two instances of rapid development, spread, and …

Keeping the momentum: suggestions for treatment policy updates in the final push to eliminate malaria in India

N Valecha - Malaria Journal, 2023 - Springer
Malaria case management with prompt and effective treatment is critical to minimize
morbidity and mortality, reduce transmission and to prevent the emergence and spread of …

Therapeutic efficacy of artemether–lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria from three highly malarious states in India

PK Bharti, MM Shukla, P Ringwald, S Krishna… - Malaria journal, 2016 - Springer
Background Anti-malarial drug resistance continues to be a leading threat to malaria control
efforts and calls for continued monitoring of waning efficacy of artemisinin-based …

Sulfadoxine-pyrimethamine resistance in Plasmodium falciparum: a zoomed image at the molecular level within a geographic context

R Abdul-Ghani, HF Farag, AF Allam - Acta tropica, 2013 - Elsevier
Antimalarial chemotherapy is one of the main pillars in the prevention and control of malaria.
Following widespread resistance of Plasmodium falciparum to chloroquine, sulfadoxine …