Pathogenesis and virulence of flavivirus infections

SW van Leur, T Heunis, D Munnur, S Sanyal - Virulence, 2021 - Taylor & Francis
The Flavivirus genus consists of> 70 members including several that are considered
significant human pathogens. Flaviviruses display a broad spectrum of diseases that can be …

Recent advances in organoid engineering: A comprehensive review

JM Unagolla, AC Jayasuriya - Applied materials today, 2022 - Elsevier
Organoid, a 3D structure derived from various cell sources including progenitor and
differentiated cells that self-organize through cell-cell and cell-matrix interactions to …

Haemorrhage of human foetal cortex associated with SARS-CoV-2 infection

M Massimo, C Barelli, C Moreno, C Collesi… - Brain, 2023 - academic.oup.com
Maternal viral infection and immune response are known to increase the risk of altered
development of the foetal brain. Given the ongoing global pandemic of coronavirus disease …

Neurocognitive impacts of arbovirus infections

M Clé, P Eldin, L Briant, A Lannuzel, Y Simonin… - Journal of …, 2020 - Springer
Arthropod-borne viruses or arbovirus, are most commonly associated with acute infections,
resulting on various symptoms ranging from mild fever to more severe disorders such as …

Pathogenesis and manifestations of Zika virus-associated ocular diseases

BA Labib, DGI Chigbu - Tropical Medicine and Infectious Disease, 2022 - mdpi.com
Zika virus (ZIKV) is mosquito-borne flavivirus that caused a significant public health concern
in French Polynesia and South America. The two major complications that gained the most …

Utility of proteomics in emerging and re-emerging infectious diseases caused by RNA viruses

M Sperk, R Van Domselaar, JE Rodriguez… - Journal of Proteome …, 2020 - ACS Publications
Emerging and re-emerging infectious diseases due to RNA viruses cause major negative
consequences for the quality of life, public health, and overall economic development. Most …

Apoptosis during ZIKA virus infection: too soon or too late?

J Turpin, D El Safadi, G Lebeau, M Krejbich… - International Journal of …, 2022 - mdpi.com
Cell death by apoptosis is a major cellular response in the control of tissue homeostasis and
as a defense mechanism in the case of cellular aggression such as an infection. Cell self …

Zika Virus NS1 Suppresses VE-Cadherin and Claudin-5 via hsa-miR-101-3p in human brain microvascular endothelial cells

U Bhardwaj, SK Singh - Molecular neurobiology, 2021 - Springer
Zika virus (ZIKV) is a neurotropic virus that causes microcephaly in newborns and Guillain-
Barré syndrome (GBS) in adults. ZIKV is known to transmigrate through the blood–brain …

Differential contributions of fetal mononuclear phagocytes to Zika virus neuroinvasion versus neuroprotection during congenital infection

M Abdelbasset, WAA Saron, D Ma, APS Rathore… - Cell, 2024 - cell.com
Fetal immune cell functions during congenital infections are poorly understood. Zika virus
(ZIKV) can vertically transmit from mother to fetus, causing nervous system infection and …

Zika virus vertical transmission induces neuroinflammation and synapse impairment in brain cells derived from children born with Congenital Zika Syndrome

C Benazzato, F Lojudice, F Pöehlchen, PEC Leite… - Scientific Reports, 2024 - nature.com
Zika virus (ZIKV) infection was first reported in 2015 in Brazil as causing microcephaly and
other developmental abnormalities in newborns, leading to the identification of Congenital …