Molecular responses to acute exercise and their relevance for adaptations in skeletal muscle to exercise training

B Egan, AP Sharples - Physiological Reviews, 2023 - journals.physiology.org
Repeated, episodic bouts of skeletal muscle contraction undertaken frequently as structured
exercise training are a potent stimulus for physiological adaptation in many organs …

Physiological adaptations to interval training and the role of exercise intensity

MJ MacInnis, MJ Gibala - The Journal of physiology, 2017 - Wiley Online Library
Interval exercise typically involves repeated bouts of relatively intense exercise interspersed
by short periods of recovery. A common classification scheme subdivides this method into …

Exercise adaptations: molecular mechanisms and potential targets for therapeutic benefit

SL McGee, M Hargreaves - Nature Reviews Endocrinology, 2020 - nature.com
Exercise is fundamental for good health, whereas physical inactivity underpins many chronic
diseases of modern society. It is well appreciated that regular exercise improves metabolism …

Training-induced changes in mitochondrial content and respiratory function in human skeletal muscle

C Granata, NA Jamnick, DJ Bishop - Sports Medicine, 2018 - Springer
A sedentary lifestyle has been linked to a number of metabolic disorders that have been
associated with sub-optimal mitochondrial characteristics and an increased risk of …

[HTML][HTML] Twelve weeks of sprint interval training improves indices of cardiometabolic health similar to traditional endurance training despite a five-fold lower exercise …

JB Gillen, BJ Martin, MJ MacInnis, LE Skelly… - PloS one, 2016 - journals.plos.org
Aims We investigated whether sprint interval training (SIT) was a time-efficient exercise
strategy to improve insulin sensitivity and other indices of cardiometabolic health to the …

Blood mitochondrial DNA copy number: what are we counting?

M Picard - Mitochondrion, 2021 - Elsevier
There is growing scientific interest to develop scalable biological measures that capture
mitochondrial (dys) function. Mitochondria have their own genome, the mitochondrial DNA …

Enhanced respiratory chain supercomplex formation in response to exercise in human skeletal muscle

C Greggio, P Jha, SS Kulkarni, S Lagarrigue… - Cell metabolism, 2017 - cell.com
Mitochondrial dysfunction is a hallmark of multiple metabolic complications. Physical activity
is known to increase mitochondrial content in skeletal muscle, counteracting age-related …

Mitochondrial dysfunction in heart failure with preserved ejection fraction

AA Kumar, DP Kelly, JA Chirinos - Circulation, 2019 - Am Heart Assoc
Heart failure with preserved ejection fraction (HFpEF) is a complex syndrome with an
increasingly recognized heterogeneity in pathophysiology. Exercise intolerance is the …

Interference between concurrent resistance and endurance exercise: molecular bases and the role of individual training variables

JJ Fyfe, DJ Bishop, NK Stepto - Sports medicine, 2014 - Springer
Concurrent training is defined as simultaneously incorporating both resistance and
endurance exercise within a periodized training regime. Despite the potential additive …

Principles of exercise prescription, and how they influence exercise-induced changes of transcription factors and other regulators of mitochondrial biogenesis

C Granata, NA Jamnick, DJ Bishop - Sports Medicine, 2018 - Springer
Physical inactivity represents the fourth leading risk factor for mortality, and it has been
linked with a series of chronic disorders, the treatment of which absorbs~ 85% of healthcare …