The measurement and clinical relevance of brain atrophy in multiple sclerosis

RA Bermel, R Bakshi - The Lancet Neurology, 2006 - thelancet.com
Brain atrophy has emerged as a clinically relevant component of disease progression in
multiple sclerosis. Progressive loss of brain tissue bulk can be detected in vivo in a sensitive …

Structural and functional imaging of normal bone marrow and evaluation of its age-related changes

JS Blebea, M Houseni, DA Torigian, C Fan… - Seminars in nuclear …, 2007 - Elsevier
A number of noninvasive imaging techniques have been used for the evaluation of bone
marrow, including magnetic resonance imaging (MRI) and bone marrow scintigraphy. The …

Age-related total gray matter and white matter changes in normal adult brain. Part I: volumetric MR imaging analysis

Y Ge, RI Grossman, JS Babb… - American journal …, 2002 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: A technique of segmenting total gray matter (GM) and total
white matter (WM) in human brain is now available. We investigated the effects of age and …

User-steered image segmentation paradigms: Live wire and live lane

AX Falcao, JK Udupa, S Samarasekera… - Graphical models and …, 1998 - Elsevier
In multidimensional image analysis, there are, and will continue to be, situations wherein
automatic image segmentation methods fail, calling for considerable user assistance in the …

Regularised marching tetrahedra: improved iso-surface extraction

GM Treece, RW Prager, AH Gee - Computers & Graphics, 1999 - Elsevier
Marching cubes is a simple and popular method for extracting iso-surfaces from implicit
functions or discrete three-dimensional (3-D) data. However, it does not guarantee the …

Multiple sclerosis lesion quantification using fuzzy-connectedness principles

JK Udupa, L Wei, S Samarasekera… - … on medical imaging, 1997 - ieeexplore.ieee.org
Multiple sclerosis (MS) is a disease of the white matter. Magnetic resonance imaging (MRI)
is proven to be a sensitive method of monitoring the progression of this disease and of its …

Scale-based fuzzy connected image segmentation: theory, algorithms, and validation

PK Saha, JK Udupa, D Odhner - Computer Vision and Image …, 2000 - Elsevier
This paper extends a previously reported theory and algorithms for object definition based
on fuzzy connectedness. In this approach, a strength of connectedness is determined …

Brain atrophy in mild or moderate traumatic brain injury: a longitudinal quantitative analysis

JD MacKenzie, F Siddiqi, JS Babb… - American Journal …, 2002 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Although mild or moderate traumatic brain injury (TBI) is
known to cause persistent neurologic sequelae, the underlying structural changes remain …

Upper airway size analysis by magnetic resonance imaging of children with obstructive sleep apnea syndrome

R Arens, JM McDonough, AM Corbin… - American journal of …, 2003 - atsjournals.org
Detailed analysis of the upper airway has not been performed in children with obstructive
sleep apnea. We used magnetic resonance imaging and automatic segmentation to …

Structural MR image processing using the BRAINS2 toolbox

VA Magnotta, G Harris, NC Andreasen… - … Medical Imaging and …, 2002 - Elsevier
Medical imaging has opened a new door into biomedical research. In order to study various
diseases of the brain and detect their impact on brain structure, robust and user friendly …