The far-reaching scope of neuroinflammation after traumatic brain injury

DW Simon, MJ McGeachy, H Bayır, RSB Clark… - Nature Reviews …, 2017 - nature.com
The'silent epidemic'of traumatic brain injury (TBI) has been placed in the spotlight as a result
of clinical investigations and popular press coverage of athletes and veterans with single or …

Advances in the development of biomarkers for epilepsy

A Pitkänen, W Löscher, A Vezzani, AJ Becker… - The Lancet …, 2016 - thelancet.com
Over 50 million people worldwide have epilepsy. In nearly 30% of these cases, epilepsy
remains unsatisfactorily controlled despite the availability of over 20 antiepileptic drugs …

Commonalities in epileptogenic processes from different acute brain insults: Do they translate?

P Klein, R Dingledine, E Aronica, C Bernard… - …, 2018 - Wiley Online Library
The most common forms of acquired epilepsies arise following acute brain insults such as
traumatic brain injury, stroke, or central nervous system infections. Treatment is effective for …

Epileptogenesis

A Pitkänen, K Lukasiuk… - Cold Spring …, 2015 - perspectivesinmedicine.cshlp.org
Epileptogenesis is a chronic process that can be triggered by genetic or acquired factors,
and that can continue long after epilepsy diagnosis. In 2015, epileptogenesis is not a …

Brain neurotrauma: molecular, neuropsychological, and rehabilitation aspects

FH Kobeissy - 2015 - books.google.com
With the contribution from more than one hundred CNS neurotrauma experts, this book
provides a comprehensive and up-to-date account on the latest developments in the area of …

[HTML][HTML] Traumatic brain injury and epilepsy: underlying mechanisms leading to seizure

BP Lucke-Wold, L Nguyen, RC Turner, AF Logsdon… - Seizure, 2015 - Elsevier
Post-traumatic epilepsy continues to be a major concern for those experiencing traumatic
brain injury. Post-traumatic epilepsy accounts for 10–20% of epilepsy cases in the general …

IL‐1β associations with posttraumatic epilepsy development: A genetics and biomarker cohort study

ML Diamond, AC Ritter, MD Failla, JA Boles… - …, 2014 - Wiley Online Library
Objective Posttraumatic epilepsy (PTE) is a significant complication following traumatic brain
injury (TBI), yet the role of genetic variation in modulating PTE onset is unclear. We …

The role of adenosine in epilepsy

L Weltha, J Reemmer, D Boison - Brain research bulletin, 2019 - Elsevier
Adenosine is a well-characterized endogenous anticonvulsant and seizure terminator of the
brain. Through a combination of adenosine receptor-dependent and-independent …

Post-traumatic epilepsy and comorbidities: advanced models, molecular mechanisms, biomarkers, and novel therapeutic interventions

VM Golub, DS Reddy, C France - Pharmacological reviews, 2022 - Elsevier
Post-traumatic epilepsy (PTE) is one of the most devastating long-term, network
consequences of traumatic brain injury (TBI). There is currently no approved treatment that …

Incidence and risk factors of posttraumatic seizures following traumatic brain injury: a traumatic brain injury model systems study

AC Ritter, AK Wagner, A Fabio, MJ Pugh… - …, 2016 - Wiley Online Library
Objective Determine incidence of posttraumatic seizure (PTS) following traumatic brain
injury (TBI) among individuals with moderate‐to‐severe TBI requiring rehabilitation and …