Electroporation designates the use of short high‐voltage pulses to overcome the barrier of
the cell membrane. By applying an external electric field, which just surpasses the …

Introduction: Electroporation allows efficient delivery of DNA into cells and tissues, thereby
improving the expression of therapeutic or immunogenic proteins that are encoded by …

Nucleic acids, such as messenger RNAs, antisense oligonucleotides, and short interfering
RNAs, hold great promise for treating previously 'undruggable'diseases. However, there are …

The success of gene therapy is largely dependent on the development of the gene delivery
vector. Recently, gene transfection into target cells using naked DNA, which is a simple and …

The current COVID‐19 pandemic has a tremendous impact on daily life world‐wide. Despite
the ability to dampen the spread of SARS‐CoV‐2, the causative agent of the diseases …

Increases in efficiency have made naked DNA gene transfer a viable method for gene
therapy. Intravascular delivery results in effective gene delivery to liver and muscle, and …

Membrane electroporation is the method to directly transfer bioactive substances such as
drugs and genes into living cells, as well as preceding electrofusion. Although much …

In recent years, DNA vaccines have undergone a number of technological advancements
that have incited renewed interest and heightened promise in the field. Two such …

In vivo electroporation (EP) is a versatile delivery method for gene transfer which can be
applied to any accessible tissue. Delivery of plasmid DNA encoding therapeutic genes or …

Historically, the skin was thought to be a simple homogenous barrier. However, it is now
known to be a highly specialised organ, and plays a key role in homeostasis. The protective …