Structure-activity relationship (SAR) study and design strategies of nitrogen-containing heterocyclic moieties for their anticancer activities
The present review article offers a detailed account of the design strategies employed for the
synthesis of nitrogen-containing anticancer agents. The results of different studies describe …
synthesis of nitrogen-containing anticancer agents. The results of different studies describe …
Quinoline anticancer agents active on DNA and DNA-interacting proteins: From classical to emerging therapeutic targets
Quinoline is one of the most important and versatile nitrogen heterocycles embodied in
several biologically active molecules. Within the numerous quinolines developed as …
several biologically active molecules. Within the numerous quinolines developed as …
Coordination behavior of new bis (tridentate ONO, ONS and ONN) donor hydrazones towards some transition metal ions: Synthesis, spectral, thermal, antimicrobial …
M Shebl - Journal of Molecular Structure, 2017 - Elsevier
Three new hydrazone ligands, H 2 L 1, H 2 L 2 and H 4 L 3, were prepared by condensation
of 4, 6-bis (1-hydrazonoethyl) benzene-1, 3-diol with furan-2-carboxaldehyde, thiophene-2 …
of 4, 6-bis (1-hydrazonoethyl) benzene-1, 3-diol with furan-2-carboxaldehyde, thiophene-2 …
Mixed-ligand Cu (II) hydrazone complexes designed to enhance anticancer activity
QY Mo, JG Deng, Y Liu, GD Huang, ZW Li, P Yu… - European Journal of …, 2018 - Elsevier
The ligand quantity, ligand type, and coordination geometry have important influences on
the anticancer activity of metal-based complexes. On the basis of the structures of previously …
the anticancer activity of metal-based complexes. On the basis of the structures of previously …
Synthesis, characterization, in vitro antimicrobial and cytotoxic evaluation of Co (II), Ni (II), Cu (II) and Zn (II) complexes derived from bidentate hydrazones
Abstract Co (II), Ni (II), Cu (II) and Zn (II) complexes have been synthesized from hydrazone
ligands (HL 1–HL 4) obtained by condensation reaction of 6-chlorothiochroman-4-one with …
ligands (HL 1–HL 4) obtained by condensation reaction of 6-chlorothiochroman-4-one with …
Chemodynamic therapy agents Cu (II) complexes of quinoline derivatives induced ER stress and mitochondria-mediated apoptosis in SK-OV-3 cells
WY Shen, CP Jia, AN Mo, H Liang, ZF Chen - European Journal of …, 2021 - Elsevier
Three Cu (II) complexes of quinoline derivatives as cancer chemodynamic therapy agents
were synthesized and characterized. These complexes were heavily taken up by cells and …
were synthesized and characterized. These complexes were heavily taken up by cells and …
Synthesis, spectral, magnetic, DFT calculations, antimicrobial studies and phenoxazinone synthase biomimetic catalytic activity of new binary and ternary Cu (II), Ni (II) …
New mononuclear copper (II), nickel (II) and cobalt (II) hydrazone complexes of 2-cyano-N′-
((4-oxo-4H-chromen-3-yl) methylene) acetohydrazide have been synthesized. Structure …
((4-oxo-4H-chromen-3-yl) methylene) acetohydrazide have been synthesized. Structure …
Synthesis and computational studies of novel cobalt (II) and oxovanadium (IV) complexes of quinoline carbaldehyde derivative ligand for antibacterial and antioxidant …
Novel metal complexes [Co (HL) 2 (H 2 O) 2)](1) and [VO (HL) 2](2) were synthesized using
2-((2-hydroxyethyl) amino) quinoline-3-carbaldehyde, ligand in 1: 2 metal–ligand ratio in …
2-((2-hydroxyethyl) amino) quinoline-3-carbaldehyde, ligand in 1: 2 metal–ligand ratio in …
Interaction of ferrocene appended Ru (II), Rh (III) and Ir (III) dipyrrinato complexes with DNA/protein, molecular docking and antitumor activity
Efficacy of the ferrocene appended piano-stool dipyrrinato complexes [(η 6-C 6 H 6) RuCl
(fcdpm)](1),[(η 6-C 10 H 14) RuCl (fcdpm)](2),[(η 6-C 12 H 18) RuCl (fcdpm)](3)[(η 5-C 5 Me …
(fcdpm)](1),[(η 6-C 10 H 14) RuCl (fcdpm)](2),[(η 6-C 12 H 18) RuCl (fcdpm)](3)[(η 5-C 5 Me …
Synthesis, cytotoxicity and DNA binding of novel Ni (II), Co (II) and Zn (II) complexes bearing pyrimidinyl hydrazone ligand
J Yuan, JY Song, HH Yang, HR Lan, AP Xing… - Journal of Molecular …, 2023 - Elsevier
To develop efficient new antitumor agents, Ni (II), Co (II) and Zn (II) complexes 1–3 derived
from 2-((2-pyrimidin-2-yl) hydrazono) methyl) quinoline (HL) were prepared and structurally …
from 2-((2-pyrimidin-2-yl) hydrazono) methyl) quinoline (HL) were prepared and structurally …