One carbon metabolism and its implication in health and immune functions

S Dang, A Jain, G Dhanda… - Cell Biochemistry …, 2024 - Wiley Online Library
One carbon (1C) metabolism is critical for cellular viability and physiological homeostasis.
Starting from its crucial involvement in purine biosynthesis to posttranslational modification …

[HTML][HTML] Identification and analysis of oncogenic non-synonymous single nucleotide polymorphisms in the human NRAS gene: An exclusive in silico study

M Mozibullah, HE Seyedi, M Khatun… - Journal of Genetic …, 2024 - Elsevier
Background N-ras protein is encoded by the NRAS gene and operates as GDP-GTP-
controlled on/off switching. N-ras interacts with cellular signaling networks that regulate …

In-silico assessment of the potential impact of missense SNPs in SYNE4 and SUN1 on the LINC complex and their association with hearing loss

M Toure, S Redouane, H Charoute, A Malki, H Rouba… - Human Gene, 2024 - Elsevier
The LINC complex plays a significant role in the auditory system, as it participates in
maintaining proper positioning and survival of the nucleus within the outer hair cells. To …

Identifying Oncogenic Missense Single Nucleotide Polymorphisms in Human SAT1 Gene Using Computational Algorithms and Molecular Dynamics Tools

M Mozibullah, M Khatun, MA Sikder, MJ Islam… - Cancer …, 2024 - Wiley Online Library
Background The human SAT1 gene encodes spermidine/spermine N1‐acetyltransferase 1
(SSAT1), a regulatory biological catalyst of polyamine catabolism. Numerous essential …

High expression of COL1A1 exaggerates bone metastasis in estrogen receptor-positive (ER+) breast cancer and is potential to serve as a novel therapeutic target

Y Tan, Y Fan - 2022 - researchsquare.com
Bone metastasis accounts for a frequent complication in advanced estrogen receptor-
positive (ER+) breast cancer, with staggeringly high percentage up to 70%. However, our …